Triclopyr

Triclopyr

SCHEMBL3219703

COc1ccccc1C(=O)NS(=O)(=O)c1ccc(C(=O)NC2CC2)cc1.O=C(O)COc1nc(Cl)c(Cl)cc1Cl

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.42
KCNA3 P22001 1/20 0.42
FLT1 P17948 1/20 0.41
FLT4 P35916 1/20 0.41
KDR P35968 1/20 0.41
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
ABCC3 O15438 1/20 0.40
ABCC4 O15439 1/20 0.40
ABCC9 O60706 1/20 0.40
ABCB11 O95342 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
CFTR P13569 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120129 0.82 KCNA3 (0.52) KCNA3FLT1FLT4KDRKMT2A
SCHEMBL29687002 0.82 KCNA3 (0.52) KCNA3FLT1FLT4KDRKMT2A
SCHEMBL3655826 0.82 KCNA3 (0.52) KCNA3FLT1FLT4KDRKMT2A
Clopyralid SCHEMBL3215470 0.80 KMT2A (0.44) KCNA3FLT1FLT4KDRKMT2A
3,6 Dichloromethoxybenzoic Acid SCHEMBL3224960 0.78 KCNA3 (0.44) KCNA3FLT1FLT4KDRKMT2A
Glyphosate SCHEMBL3221805 0.78 L3MBTL1 (0.47) L3MBTL1KCNA3KMT2AMEN1LMNA
Picloram SCHEMBL3231524 0.78 KCNA3 (0.41) KCNA3FLT1FLT4KDRKMT2A
SCHEMBL3221168 0.77 KMT2A (0.38) L3MBTL1KCNA3KMT2AMEN1ABCC3
Propanil SCHEMBL3225616 0.76 KDM4E (0.54) KMT2AMEN1ALDH1A1LMNACYP1A2
SCHEMBL31249658 0.76 HSD17B10 (0.53) KMT2AMEN1ALDH1A1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100234227-A1 MICROEMULSION CONCENTRATES BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed
US-20100048516-A1 PENETRATION ENHANCER FOR FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-02-25 US disclosed
US-20080176746-A1 avoids antagonistically reduced activity or overdosage otherwise requiring split applications; by employing an oil suspension concentrate BAYER CROPSCIENCE AG (DE) 2008-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048516-A1 PENETRATION ENHANCER FOR FUNGICIDES DDT, DCPS, TYMP L3MBTL1 2389/4885KCNA3 1522/4885FLT1 1523/4885
US-20080176746-A1 avoids antagonistically reduced activity or overdosage otherwise requiring split applications; by employing an oil suspension concentrate LIPA, MGLL, ABHD6 L3MBTL1 1025/4885KCNA3 4830/4885FLT1 4736/4885
US-20100234227-A1 MICROEMULSION CONCENTRATES ADH1C, MGLL, ADH1A L3MBTL1 2824/4885KCNA3 3382/4885FLT1 3256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.