Propanil

Propanil

SCHEMBL3225616

CCC(=O)Nc1ccc(Cl)c(Cl)c1.COc1ccccc1C(=O)NS(=O)(=O)c1ccc(C(=O)NC2CC2)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.54
CXCR6 O00574 1/20 0.45
CYSLTR1 Q9Y271 3/20 0.44
EPHX2 P34913 2/20 0.44
PPARG P37231 2/20 0.44
TSHR P16473 1/20 0.44
MAPT P10636 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
POLB P06746 1/20 0.44
MAPK1 P28482 1/20 0.44
CYP3A4 P08684 2/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
SMYD3 Q9H7B4 1/20 0.43
BCL2L1 Q07817 1/20 0.43
MCL1 Q07820 1/20 0.43
KCNA5 P22460 1/20 0.43
CYSLTR2 Q9NS75 1/20 0.43
CHRM5 P08912 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120129 0.83 KCNA3 (0.52) MEN1KMT2ALMNA
SCHEMBL3655826 0.83 KCNA3 (0.52) MEN1KMT2ALMNA
SCHEMBL29687002 0.83 KCNA3 (0.52) MEN1KMT2ALMNA
SCHEMBL4336890 0.81 THRB (0.47) KDM4ECYSLTR1EPHX2PPARGTSHR
SCHEMBL626675 0.80 KMT2A (0.48) KDM4ECYSLTR1EPHX2PPARGMAPT
3,6 Dichloromethoxybenzoic Acid SCHEMBL3224960 0.79 KCNA3 (0.44) KDM4EPPARGTSHRMAPTMEN1
Clopyralid SCHEMBL3215470 0.78 KMT2A (0.44) PPARGTSHRMAPTMEN1KMT2A
SCHEMBL31249658 0.77 HSD17B10 (0.53) MEN1KMT2AALDH1A1LMNA
Triclopyr SCHEMBL3219703 0.76 L3MBTL1 (0.42) PPARGTSHRMAPTMEN1KMT2A
SCHEMBL12831717 0.76 NLRP3 (0.61) PPARGTSHRMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100234227-A1 MICROEMULSION CONCENTRATES BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed
US-20100048516-A1 PENETRATION ENHANCER FOR FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-02-25 US disclosed
US-20080176746-A1 avoids antagonistically reduced activity or overdosage otherwise requiring split applications; by employing an oil suspension concentrate BAYER CROPSCIENCE AG (DE) 2008-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048516-A1 PENETRATION ENHANCER FOR FUNGICIDES DDT, DCPS, TYMP KDM4E 869/4885CXCR6 3911/4885CYSLTR1 4771/4885
US-20080176746-A1 avoids antagonistically reduced activity or overdosage otherwise requiring split applications; by employing an oil suspension concentrate LIPA, MGLL, ABHD6 KDM4E 3886/4885CXCR6 2463/4885CYSLTR1 4056/4885
US-20100234227-A1 MICROEMULSION CONCENTRATES ADH1C, MGLL, ADH1A KDM4E 3160/4885CXCR6 4034/4885CYSLTR1 4309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.