Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5891888 | 0.79 | BCL2 (0.37) | ALDH1A1MAPK1HSD11B1MEN1KMT2A | |
| SCHEMBL812199 | 0.78 | ACHE (0.39) | ALDH1A1CYP2D6CYP2C19CYP1A2MAPK1 | |
| SCHEMBL3220633 | 0.77 | TSHR (0.44) | ALDH1A1TSHRKCNN4CYP2D6CYP2C19 | |
| SCHEMBL28467487 | 0.76 | CYP2D6 (0.44) | ALDH1A1KCNN4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL812200 | 0.74 | ACHE (0.36) | ALDH1A1TSHRCA1CA2CA9 | |
| SCHEMBL1336610 | 0.73 | KCNN4 (0.56) | ALDH1A1TSHRKCNN4CA1CA2 | |
| SCHEMBL5250544 | 0.71 | KCNN4 (0.48) | ALDH1A1TSHRKCNN4CA1CA2 | |
| SCHEMBL3972409 | 0.70 | TSHR (0.52) | ALDH1A1TSHRKCNN4CA1CA2 | |
| SCHEMBL12356881 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRKCNN4CA1CA2 | |
| SCHEMBL19448773 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRKCNN4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439170-B1 | Fluorinating reactants and process for their preparation | SALTIGO GMBH (DE) | 2009-06-03 | — | — | EP | claimed |
| US-20040198975-A1 | Alpha, alpha-difluoroamines and difluoromethylene-alpha, alpha-diazo compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | US | claimed |
| EP-1439170-A1 | Fluorinating reactants and process for their preparation | Bayer Chemicals AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | LANXESS DEUTSCHLAND GMBH (DE) | 2010-02-11 | — | — | US | disclosed |
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | LANXESS DEUTSCHLAND GMBH (DE) | 2010-02-11 | — | — | US | disclosed |
| EP-1439170-B1 | Fluorinating reactants and process for their preparation | SALTIGO GMBH (DE) | 2009-06-03 | — | — | EP | disclosed |
| US-7045662-B2 | α, α-difluoroamines and difluoromethylene-α, α-diazo compounds | BAYER CHEMICALS AG (DE) | 2006-05-16 | — | — | US | disclosed |
| US-20050085474-A1 | Fluorinating reagents and their preparation | LANXESS DEUTSCHLAND GMBH (DE) | 2005-04-21 | — | — | US | disclosed |
| US-20040198975-A1 | Alpha, alpha-difluoroamines and difluoromethylene-alpha, alpha-diazo compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | US | disclosed |
| EP-1439170-A1 | Fluorinating reactants and process for their preparation | Bayer Chemicals AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| EP-1437342-A2 | Fluorinating reactants and process for their preparation | Bayer Chemicals AG (DE) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198975-A1 | Alpha, alpha-difluoroamines and difluoromethylene-alpha, alpha-diazo compounds | DDT, DDO, SAT1 | ALDH1A1 365/4885TSHR 2122/4885KCNN4 4383/4885 |
| US-20050085474-A1 | Fluorinating reagents and their preparation | FLNA, ARFGEF1, FLNB | ALDH1A1 362/4885TSHR 1608/4885KCNN4 4717/4885 |
| US-20100036119-A1 | FLUORINATING REAGENTS AND THEIR PREPARATION | FLNA, ARFGEF1, FLNB | ALDH1A1 362/4885TSHR 1608/4885KCNN4 4717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.