Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223142 | 0.78 | ALDH1A1 (0.44) | KIF11CYP3A4CYP2D6CYP2C19MEN1 | |
| SCHEMBL295494 | 0.74 | LMNA (0.40) | ACHEPTPN5CETPKIF11CYP3A4 | |
| SCHEMBL822098 | 0.73 | ACHE (0.52) | ACHEPTPN5KIF11CYP3A4CYP2D6 | |
| SCHEMBL148048 | 0.73 | NFE2L2 (0.55) | ACHEPTPN5CETPKIF11HTR2A | |
| SCHEMBL24342189 | 0.73 | PTPN5 (0.44) | ACHEPTPN5CETPKIF11CYP3A4 | |
| SCHEMBL14366432 | 0.73 | LMNA (0.39) | ACHEPTPN5CETPKIF11CYP3A4 | |
| SCHEMBL18891585 | 0.71 | ACHE (0.50) | ACHEPTPN5KIF11CYP3A4CYP2D6 | |
| Bromide SCHEMBL27462091 | 0.71 | NFE2L2 (0.53) | ACHEPTPN5CETPKIF11HTR2A | |
| Ammonia Solution, Strong SCHEMBL1869257 | 0.71 | NFE2L2 (0.53) | ACHEPTPN5CETPKIF11HTR2A | |
| SCHEMBL8242617 | 0.71 | ACHE (0.50) | ACHEPTPN5KIF11CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968751-B2 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-7892518-B2 | fluorinating a specific position of a saccharide substrate selectively without affecting a protective group at a temperature within a wide range safely and easily with N, N-diethyl-alpha, alpha-difluoro(3-methyl)benzylamine a fluorinating agent under irradiation with microwave or electromagnetic wave | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-02-22 | — | — | US | disclosed |
| EP-2189467-A2 | Method of fluorination by microwaves | Mitsubishi Gas Chemical Company, Inc. (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-2189466-A2 | METHOD OF FLUORINATION BY MICROWAVES | Mitsubishi Gas Chemical Company, Inc. (JP) | 2010-05-26 | — | — | EP | disclosed |
| US-20080319228-A1 | Method of fluorination | HARA SHOJI | 2008-12-25 | — | — | US | disclosed |
| US-20080154064-A1 | Method of fluorination | HARA SHOJI | 2008-06-26 | — | — | US | disclosed |
| US-7351863-B2 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20060014972-A1 | Method of fluorination | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-01-19 | — | — | US | disclosed |
| EP-1568703-A1 | METHOD OF FLUORINATION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080154064-A1 | Method of fluorination | FUCA2, FABP2, FGB | ACHE 3090/4885PTPN5 4817/4885CETP 218/4885 |
| US-20080319228-A1 | Method of fluorination | FUCA2, FABP2, FGB | ACHE 3090/4885PTPN5 4817/4885CETP 218/4885 |
| US-20060014972-A1 | Method of fluorination | FUCA2, FABP2, FGB | ACHE 3090/4885PTPN5 4817/4885CETP 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.