Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.68 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.68 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167259 | 0.95 | PRSS1 (0.74) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL308555 | 0.92 | PRSS1 (0.60) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL5918234 | 0.87 | ALDH1A1 (0.80) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL21835102 | 0.86 | LMNA (0.84) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| Octisalate SCHEMBL1946017 | 0.85 | LMNA (0.73) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| Octisalate SCHEMBL29428934 | 0.85 | LMNA (0.73) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL11326963 | 0.85 | ALDH1A1 (0.76) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| Bis(2-Ethylhexyl) Phthalate SCHEMBL6245567 | 0.85 | PRSS1 (0.85) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| Bis(2-Ethylhexyl) Phthalate SCHEMBL9473452 | 0.85 | PRSS1 (0.85) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| Bis(2-Ethylhexyl) Phthalate SCHEMBL8498138 | 0.85 | PRSS1 (0.85) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100084-A1 | POLYMERS BASED ON ARCRYLIC, METHACRYLIC OR ETHACRYLIC AMIDOALKYL SULFONIC ACID OR SALTS AND CARBOXYALKY ACRYLATE, METHACRYLATE OR ETHACRYLATE OR OLIGOMERS OF SAID CARBOXY COMPOUNDS | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-04-26 | — | — | US | disclosed |
| US-20110229427-A1 | Phosphoric Acid Esters Containing Phosphorus Atoms Bridged By Polyol Units | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-09-22 | — | — | US | disclosed |
| US-20110130704-A1 | COMBINATION OF A LIGHT RAY AND A LIPASE-BIOCONVERTIBLE COMPOUND FOR IMPROVING SKIN AND/OR HAIR APPEARANCE | L'OREAL (FR) | 2011-06-02 | — | — | US | disclosed |
| US-20110104085-A1 | Cosmetic Or Pharmaceutical Compositions Comprising Modified Polysiloxanes With At Least One Carbamate Group | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-05-05 | — | — | US | disclosed |
| US-20110003010-A1 | Phosphoric Acid Esters Containing Phosphorus Atoms Bridged By Diol Units | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-01-06 | — | — | US | disclosed |
| US-20060104940-A1 | Cosmetic, pharmaceutical and dermatological preparations comprising copolymer waxes | CLARIANT GMBH | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100084-A1 | POLYMERS BASED ON ARCRYLIC, METHACRYLIC OR ETHACRYLIC AMIDOALKYL SULFONIC ACID OR SALTS AND CARBOXYALKY ACRYLATE, METHACRYLATE OR ETHACRYLATE OR OLIGOMERS OF SAID CARBOXY COMPOUNDS | ASS1, ADSL, ACMSD | PRSS1 1424/4885PRSS2 1243/4885PRSS3 2384/4885 |
| US-20060104940-A1 | Cosmetic, pharmaceutical and dermatological preparations comprising copolymer waxes | CUTA, ACMSD, DEGS1 | PRSS1 2629/4885PRSS2 3397/4885PRSS3 3210/4885 |
| US-20110003010-A1 | Phosphoric Acid Esters Containing Phosphorus Atoms Bridged By Diol Units | HAO2, HAO1, CYP24A1 | PRSS1 4610/4885PRSS2 4616/4885PRSS3 4812/4885 |
| US-20110104085-A1 | Cosmetic Or Pharmaceutical Compositions Comprising Modified Polysiloxanes With At Least One Carbamate Group | KDM1A, KDM6A, KDM2A | PRSS1 2440/4885PRSS2 2778/4885PRSS3 2385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.