Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3225817 | 0.76 | CYP2A6 (0.44) | MAOBMAOA | |
| SCHEMBL6761014 | 0.74 | ALDH1A1 (0.42) | NFE2L2HSD11B1APPPTGS1FBP1 | |
| SCHEMBL3230155 | 0.74 | CYP2A6 (0.46) | NFE2L2PTGS1FBP1MAOB | |
| SCHEMBL3227490 | 0.74 | HSD17B10 (0.46) | FBP1MAOB | |
| SCHEMBL3228392 | 0.74 | ALDH5A1 (0.46) | NFE2L2HSD11B1APPPTGS1MAOB | |
| SCHEMBL3222382 | 0.74 | APP (0.44) | APPMAOBMAOA | |
| SCHEMBL11220322 | 0.73 | VCP (0.46) | MAOBMAOA | |
| SCHEMBL3219279 | 0.73 | HDAC3 (0.44) | PTGS1FBP1MAOB | |
| SCHEMBL10544388 | 0.73 | CRHBP (0.36) | NFE2L2 | |
| SCHEMBL334039 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | CHRM1, PRDX1, CHRM2 | NFE2L2 2514/4885HSD11B1 4263/4885METAP1 1846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.