Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.41 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.41 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314621 | 1.00 | CA1 (0.41) | CA1CA2CA9ALDH1A1HSD17B10 | |
| Water SCHEMBL29022567 | 0.98 | CA1 (0.40) | CA1CA2CA9ALDH1A1HSD17B10 | |
| Water SCHEMBL31290685 | 0.98 | CA1 (0.40) | CA1CA2CA9ALDH1A1HSD17B10 | |
| Formaldehyde SCHEMBL9143924 | 0.96 | CA1 (0.39) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL31214954 | 0.96 | CA1 (0.41) | CA1CA2CA9ALDH1A1HSD17B10 | |
| Lithium Ion SCHEMBL5016628 | 0.96 | CA1 (0.41) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL30108990 | 0.96 | CA1 (0.41) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL11104505 | 0.96 | CA1 (0.41) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL30108865 | 0.96 | CA1 (0.41) | CA1CA2CA9ALDH1A1HSD17B10 | |
| Potassium Ion SCHEMBL10726076 | 0.96 | CA1 (0.41) | CA1CA2CA9ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745168-B2 | Method for selectively staining chitin-containing organisms | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-06-29 | — | — | US | claimed |
| US-7157242-B1 | Method for staining fungi and protozoa | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-01-02 | — | — | US | claimed |
| CN-112694843-A | Adhesive impact absorbing layer and laminate comprising same | 日进材料股份有限公司 | 2021-04-23 | — | — | CN | disclosed |
| US-7157242-B1 | Method for staining fungi and protozoa | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-01-02 | — | — | US | disclosed |
| US-5670294-A | ALKALI METAL SILICATE, SURFACTANT | IMATION CORP (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0732628-A1 | Aqueous alkaline solution for developing offset printing plate | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-09-18 | — | — | EP | disclosed |
| US-4186006-A | AQUEOUS DEVELOPER OF BENZYL ALCOHOL, A-METHYL-BENZYL ALCOHOL, PHENOXYETHANAL OR BENZYLOXYETHANOL, ANIONIC SURFACTANT, AND WATER-SOLUBLE SULFITE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-01-29 | — | — | US | disclosed |
| US-3961052-A | NITROGEN HETEROCYCLES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-01 | — | — | US | disclosed |