Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063146 | 0.79 | CACNA1I (0.34) | HTR2AHTR2CKCNH2 | |
| SCHEMBL1063145 | 0.79 | CACNA1I (0.34) | HTR2AHTR2CKCNH2 | |
| SCHEMBL16935058 | 0.77 | HRH3 (0.34) | KCNH2 | |
| SCHEMBL29721716 | 0.76 | DAO (0.40) | DAOHTR2AHTR2CKCNH2 | |
| SCHEMBL4024505 | 0.75 | AGBL2 (0.31) | — | |
| SCHEMBL3946534 | 0.75 | APLNR (0.37) | — | |
| SCHEMBL21063772 | 0.72 | RIPK1 (0.37) | HTR2AHTR2C | |
| SCHEMBL3038288 | 0.71 | L3MBTL1 (0.33) | — | |
| SCHEMBL17981982 | 0.70 | SCN9A (0.37) | — | |
| SCHEMBL2860573 | 0.70 | DAO (0.41) | DAOKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020810-A1 | 2-(IMIDAZ0LYLAMIN0)-PYRIDINE DERIVATIVES AND THEIR USE AS JAK KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-02-25 | — | — | WO | disclosed |