Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | VEGFA | P15692 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458853 | 0.88 | TDP1 (0.41) | RAPGEF4PKML3MBTL1HTT | |
| SCHEMBL4827468 | 0.79 | RAPGEF4 (0.55) | RAPGEF4PKMCA1CA2VEGFA | |
| SCHEMBL5776529 | 0.75 | RAPGEF4 (0.56) | RAPGEF4PKMCA1CA2L3MBTL1 | |
| SCHEMBL9991194 | 0.72 | L3MBTL1 (0.44) | RAPGEF4PKMCA1CA2VEGFA | |
| SCHEMBL30892366 | 0.70 | L3MBTL1 (0.50) | RAPGEF4PKMCA1CA2L3MBTL1 | |
| SCHEMBL3188642 | 0.70 | RAPGEF4 (0.61) | RAPGEF4PKMCA1CA2L3MBTL1 | |
| SCHEMBL3834757 | 0.69 | RAPGEF4 (0.65) | RAPGEF4PKMCA1CA2L3MBTL1 | |
| SCHEMBL29179097 | 0.69 | RAPGEF4 (0.74) | RAPGEF4PKMCA1CA2VEGFA | |
| SCHEMBL16540512 | 0.69 | RAPGEF4 (0.56) | RAPGEF4PKMCA1CA2VEGFA | |
| SCHEMBL10017637 | 0.67 | TLR9 (0.47) | CA1CA2C5AR1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140031562-A1 | Method for Forming Allylic Alcohols | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI (US) | 2014-01-30 | — | — | US | disclosed |
| US-20140031562-A1 | Method for Forming Allylic Alcohols | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI (US) | 2014-01-30 | — | — | US | disclosed |
| WO-2010025366-A2 | METHOD FOR FORMING ALLYLIC ALCOHOLS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031562-A1 | Method for Forming Allylic Alcohols | ADH1A, ADH1C, ADH5 | RAPGEF4 1098/4885PKM 1661/4885CA1 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.