SCHEMBL3240736

SCHEMBL3240736

O=S(=O)(c1ccccc1)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.47
MCOLN3 Q8TDD5 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
ENPP3 O14638 1/20 0.40
ENPP1 P22413 1/20 0.40
ENPP2 Q13822 1/20 0.40
DUSP3 P51452 1/20 0.40
PTPN5 P54829 1/20 0.40
PTPN11 Q06124 1/20 0.40
FAAH O00519 1/20 0.40
HTR6 P50406 1/20 0.39
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
FPR1 P21462 1/20 0.39
ALDH1A1 P00352 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3454878 0.77 KMT2A (0.40) GAAMCOLN3SMN1; SMN2NPC1RAB9A
SCHEMBL21923025 0.77 GBA1 (0.44) SMN1; SMN2NPC1RAB9AKMT2ACA2
SCHEMBL28433748 0.76 GAA (0.56) GAAMCOLN3SMN1; SMN2CA2CA9
SCHEMBL22026800 0.72 GAA (0.52) GAAMCOLN3SMN1; SMN2RAB9AKMT2A
SCHEMBL30946664 0.72 SMN1; SMN2 (0.53) GAASMN1; SMN2KMT2ACA2CA9
SCHEMBL3246617 0.72 CA1 (0.47) KMT2ACA2CA9HTR6CNR1
SCHEMBL3239648 0.72 HSD11B1 (0.48) SMN1; SMN2NPC1RAB9AKMT2ACA2
SCHEMBL812701 0.72 LMNA (0.71) SMN1; SMN2NPC1RAB9AKMT2ACA2
SCHEMBL28527990 0.72 ENPP3 (0.50) GAAMCOLN3SMN1; SMN2NPC1RAB9A
SCHEMBL19798460 0.72 KMT2A (0.51) GAASMN1; SMN2NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230288610-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
US-20230288610-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
EP-1167366-B1 AMINE DERIVATIVES DAIICHI SANKYO CO LTD (JP) 2010-05-05 EP disclosed
US-6562849-B1 Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. SANKYO COMPANY, LIMITED (JP) 2003-05-13 US disclosed
US-20030078426-A1 Amine derivative compounds SANKYO COMPANY, LIMITED (JP) 2003-04-24 US disclosed
EP-1167366-A1 AMINE DERIVATIVES Sankyo Company, Limited (JP) 2002-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030078426-A1 Amine derivative compounds H1-10, APOB, PRMT1 GAA 3055/4885MCOLN3 1640/4885SMN1; SMN2 3933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.