SCHEMBL3243528

SCHEMBL3243528

COc1ccccc1Oc1cc(NC(C)=O)c(F)cc1[N+](=O)[O-]

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.52
KMT2A Q03164 7/20 0.46
MEN1 O00255 6/20 0.46
POLB P06746 2/20 0.45
RAB9A P51151 1/20 0.45
ALDH1A1 P00352 6/20 0.45
TDP1 Q9NUW8 2/20 0.45
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45
HTT P42858 1/20 0.44
GAA P10253 1/20 0.43
USP2 O75604 1/20 0.43
HSPB1 P04792 1/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29929714 0.91 L3MBTL1 (0.52) L3MBTL1KMT2AMEN1POLBRAB9A
SCHEMBL3245195 0.90 KMT2A (0.45) L3MBTL1KMT2AMEN1POLBRAB9A
SCHEMBL3241043 0.88 MEN1 (0.46) L3MBTL1KMT2AMEN1POLBRAB9A
SCHEMBL3245191 0.88 KMT2A (0.43) L3MBTL1KMT2AMEN1POLBRAB9A
SCHEMBL13397203 0.87 ALDH1A1 (0.46) L3MBTL1KMT2AMEN1POLBRAB9A
SCHEMBL13397202 0.86 SMN1; SMN2 (0.46) L3MBTL1KMT2AMEN1POLBALDH1A1
SCHEMBL25095984 0.86 L3MBTL1 (0.47) L3MBTL1KMT2AMEN1POLBRAB9A
SCHEMBL3245165 0.86 ALDH1A1 (0.47) L3MBTL1KMT2AMEN1POLBALDH1A1
SCHEMBL8955420 0.83 MAPT (0.58) L3MBTL1KMT2AMEN1RAB9AALDH1A1
SCHEMBL13832507 0.82 ALDH1A1 (0.48) KMT2AMEN1POLBRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1736052-B1 Stem/leaf desiccant SUMITOMO CHEMICAL CO (JP) 2010-04-21 EP disclosed
US-7538072-B2 Stem/leaf desiccant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-26 US disclosed
US-7538072-B2 Stem/leaf desiccant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-26 US disclosed
US-7538072-B2 Stem/leaf desiccant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-26 US disclosed
EP-1397958-B1 STEM/LEAF DESICCANT SUMITOMO CHEMICAL CO (JP) 2007-01-10 EP disclosed
EP-1397958-B1 STEM/LEAF DESICCANT SUMITOMO CHEMICAL CO (JP) 2007-01-10 EP disclosed
EP-1736052-A2 Stem/leaf desiccant Sumitomo Chemical Company, Limited (JP) 2006-12-27 EP disclosed
US-20060234865-A1 Using an acylurea compound containing pyrimidine ring;; used before the harvest of crops such as potato, sunflower, soybean, rape, sorghum and the like; methyl [2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy]acetate SUMITOMO CHEMICAL COMPANY, LIMITED 2006-10-19 US disclosed
US-7115544-B2 Plant growth regulators for cotton hervest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-03 US disclosed
US-7109148-B2 Stem/leaf desiccant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-19 US disclosed
EP-1106607-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2005-07-27 EP disclosed
US-20040152597-A1 Plant growth regulators for cotton hervest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-08-05 US disclosed
US-20040138063-A1 Using an acylurea compound containing pyrimidine ring SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-07-15 US disclosed
EP-1397958-A1 STEAM/LEAF DESSICANT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-17 EP disclosed
US-6667413-B2 Aniline derivatives; herbicides; nonphytotoxic SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-23 US disclosed
US-20030130124-A1 Herbicides SUMITOMO CHEMICAL COMPANY, LIMITED 2003-07-10 US disclosed
WO-2002098227-A1 PLANT GROWTH REGULATORS FOR COTTON HERVEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-12 WO disclosed
US-6451740-B2 HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-17 US disclosed
US-20020013466-A1 Uracil compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-31 US disclosed
EP-1106607-A2 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152597-A1 Plant growth regulators for cotton hervest GHDC, CBR3, CBR1 L3MBTL1 534/4885KMT2A 923/4885MEN1 3846/4885
US-20060234865-A1 Using an acylurea compound containing pyrimidine ring;; used before the harvest of crops such as potato, sunflower, soybean, rape, sorghum and the like; methyl [2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy]acetate CPS1, H1-0, H1-3 L3MBTL1 1046/4885KMT2A 802/4885MEN1 2923/4885
US-20030130124-A1 Herbicides CBR3, CBR1, MT-CO1 L3MBTL1 295/4885KMT2A 1323/4885MEN1 3863/4885
US-20020013466-A1 Uracil compounds and use thereof UNG, MRM1, OGG1 L3MBTL1 117/4885KMT2A 2006/4885MEN1 2823/4885
US-20040138063-A1 Using an acylurea compound containing pyrimidine ring CPS1, ACACA, ODC1 L3MBTL1 116/4885KMT2A 1772/4885MEN1 4250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.