Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 10/20 | 0.70 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | TTPA | P49638 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243972 | 1.00 | PSEN1 (0.70) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL627629 | 1.00 | PSEN1 (0.70) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL13086409 | 1.00 | PSEN1 (0.70) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL10074174 | 1.00 | PSEN1 (0.70) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL627615 | 0.89 | PSEN1 (0.64) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL14393313 | 0.88 | PSEN1 (0.85) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL20107222 | 0.88 | PSEN1 (0.85) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL627937 | 0.88 | PSEN1 (0.66) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL14335452 | 0.88 | PSEN1 (0.85) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL13084628 | 0.87 | PSEN1 (0.67) | PSEN1GSTO1PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235938-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION | 2004-11-25 | — | — | US | claimed |
| EP-1254130-A4 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RES DEV FOUNDATION (US) | 2003-04-23 | — | — | EP | claimed |
| EP-1254130-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2002-11-06 | — | — | EP | claimed |
| EP-1115398-A4 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RES DEV FOUNDATION (US) | 2002-10-16 | — | — | EP | claimed |
| WO-2001058889-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2001-08-16 | — | — | WO | claimed |
| EP-1115398-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2001-07-18 | — | — | EP | claimed |
| WO-2000016772-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2000-03-30 | — | — | WO | claimed |
| US-8664264-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2014-03-04 | — | — | US | disclosed |
| US-8664264-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2014-03-04 | — | — | US | disclosed |
| US-20120251616-A1 | Tocopherols, Tocotrienols, Other Chroman and Side Chain Derivatives and Uses Thereof | SANDERS BOB G (US) | 2012-10-04 | — | — | US | disclosed |
| US-20120251616-A1 | Tocopherols, Tocotrienols, Other Chroman and Side Chain Derivatives and Uses Thereof | SANDERS BOB G (US) | 2012-10-04 | — | — | US | disclosed |
| US-8148424-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-8148424-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-7312232-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2007-12-25 | — | — | US | disclosed |
| US-7300954-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2007-11-27 | — | — | US | disclosed |
| US-20040235938-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION | 2004-11-25 | — | — | US | disclosed |
| EP-1115398-A4 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RES DEV FOUNDATION (US) | 2002-10-16 | — | — | EP | disclosed |
| US-20020107207-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION | 2002-08-08 | — | — | US | disclosed |
| EP-1115398-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000016772-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2000-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235938-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | TXN, TXN2, TTPA | PSEN1 2534/4885GSTO1 8/4885PTPN1 2222/4885 |
| US-20020107207-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | TST, HCCS, TXNRD3 | PSEN1 3859/4885GSTO1 20/4885PTPN1 2209/4885 |
| US-20120251616-A1 | Tocopherols, Tocotrienols, Other Chroman and Side Chain Derivatives and Uses Thereof | TST, TXNRD3, TXNRD1 | PSEN1 3935/4885GSTO1 40/4885PTPN1 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.