Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.36 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246493 | 0.85 | FNTA (0.39) | CYP11B2MEN1KMT2AFNTAFNTB | |
| SCHEMBL3247390 | 0.82 | GRIN2B (0.39) | CYP11B2MEN1KMT2AUSP30GRIN2B | |
| SCHEMBL3241068 | 0.82 | CYP11B2 (0.41) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL3267887 | 0.82 | MAPK1 (0.45) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL3239090 | 0.77 | GRIN2B (0.41) | GRIN2BKDM4ELMNAALDH1A1 | |
| SCHEMBL3130951 | 0.77 | ESR1 (0.43) | CYP11B2KDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3240923 | 0.76 | MET (0.38) | CYP11B2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL3128413 | 0.76 | KDM4E (0.36) | CYP11B2MEN1RAB9AKMT2AKDM4E | |
| SCHEMBL3122131 | 0.75 | MAPK1 (0.43) | MEN1RAB9AKMT2AALDH1A1CYP3A4 | |
| SCHEMBL3247305 | 0.73 | LMNA (0.41) | CYP11B2MEN1RAB9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | claimed |