Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 6/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.42 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3256693 | 0.86 | ACLY (0.40) | SCN1ASCN5ASCN8ACCR4 | |
| SCHEMBL3253952 | 0.84 | MEN1 (0.48) | SCN1ASCN5ASCN8ACYP1A2CYP3A4 | |
| SCHEMBL3256119 | 0.83 | SCN8A (0.40) | SCN1ASCN5ASCN8ACYP2D6CYP2C9 | |
| SCHEMBL3256970 | 0.83 | ALOX12 (0.46) | SCN1ASCN5ASCN8ASCN1B | |
| SCHEMBL3258919 | 0.83 | GAA (0.41) | RAB9ASCN1ASCN5ASCN8ACCR4 | |
| SCHEMBL3248733 | 0.82 | HSD11B1 (0.51) | SCN1ASCN5ASCN8ACYP3A4CCR4 | |
| SCHEMBL3253214 | 0.82 | AKT1 (0.46) | — | |
| SCHEMBL3250345 | 0.82 | ALDH1A1 (0.49) | — | |
| SCHEMBL3259074 | 0.82 | HTT (0.49) | SCN1ASCN5ASCN8ACCR4PIK3CD | |
| SCHEMBL3256778 | 0.81 | P2RY1 (0.49) | EGLN1SCN3AHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461325-B1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2010-05-26 | — | — | EP | claimed |