Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3255332 | 0.85 | ADORA3 (0.40) | HSD17B10ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL3252529 | 0.85 | ALDH1A1 (0.47) | HSD17B10ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL3245727 | 0.85 | GABRA1 (0.50) | HSD17B10ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3248921 | 0.85 | ALDH1A1 (0.41) | HSD17B10ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL3247431 | 0.84 | MAPT (0.48) | HSD17B10ALDH1A1KDM4EUSP2GAA | |
| SCHEMBL3243057 | 0.83 | CHEK1 (0.37) | HSD17B10ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL3251608 | 0.83 | JAK2 (0.47) | HSD17B10ALDH1A1KDM4EUSP2GAA | |
| SCHEMBL3249374 | 0.82 | CHEK1 (0.47) | HSD17B10ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL3241840 | 0.82 | KDM4E (0.41) | HSD17B10ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL3244745 | 0.82 | GABRA1 (0.36) | HSD17B10ALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | claimed |