Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.41 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28420653 | 1.00 | RECQL (0.50) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL27413168 | 1.00 | RECQL (0.50) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL10892598 | 1.00 | RECQL (0.50) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL2722190 | 1.00 | RECQL (0.50) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL324855 | 1.00 | RECQL (0.50) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL11424973 | 1.00 | RECQL (0.50) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL29715793 | 1.00 | RECQL (0.50) | RECQLGLAHPGDTSHRMAPK1 | |
| Potassium Ion SCHEMBL11687296 | 0.96 | RECQL (0.46) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL4324642 | 0.92 | RECQL (0.44) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL7913760 | 0.86 | RECQL (0.44) | RECQLGLAHPGDTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220203437-A1 | TUNABLE REACTIVE ALUMINUM SLURRY FUEL | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-06-30 | — | — | US | disclosed |
| US-20120167451-A1 | PYROLYSIS OIL BASED FUEL AND METHOD OF PRODUCTION | NEW GENERATION BIOFUELS HOLDINGS, INC. (US) | 2012-07-05 | — | — | US | disclosed |
| WO-2012006316-A1 | PYROLYSIS OIL BASED FUEL AND METHOD OF PRODUCTION | NEW GENERATION BIOFUELS HOLDINGS, INC. (US) | 2012-01-12 | — | — | WO | disclosed |
| US-20100037513-A1 | Biofuel Composition and Method of Producing a Biofuel | NEW GENERATION BIOFUELS, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| EP-2010631-A2 | BIOFUEL COMPOSITION AND METHOD OF PRODUCING A BIOFUEL | New Generation Biofuels, Inc. (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007127059-A2 | BIOFUEL COMPOSITION AND METHOD OF PRODUCING A BIOFUEL | NEW GENERATION BIOFUELS, INC. (US) | 2007-11-08 | — | — | WO | disclosed |
| US-6235067-B1 | LIQUID HYDROCARBON FUEL AND WATER SUPERCRITICAL MIXTURE EMITTER NOZZLES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-05-22 | — | — | US | disclosed |
| US-4078923-A | Migration imaging with surfactant-modified solvent development | XEROX CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |