Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12615992 | 0.85 | ALDH1A1 (0.68) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL30084182 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL8540440 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL7768909 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL5330184 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL28955008 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL14242848 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL436604 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL8109135 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E | |
| SCHEMBL5549180 | 0.76 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367709-B2 | Dipeptide analogs as coagulation factor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-02-05 | — | — | US | disclosed |
| US-20100173899-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2010-07-08 | — | — | US | disclosed |
| US-7679082-B2 | Multi-functional copolymers comprising rare earth metal complexes and devices thereof | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2010-03-16 | — | — | US | disclosed |
| US-20070290199-A1 | Multi-Functional Copolymers Comprising Rare Earth Metal Complexes and Devices Thereof | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2007-12-20 | — | — | US | disclosed |
| EP-0788487-B1 | PROCESS FOR THE PREPARATION OF TETRAZOLES | NOVARTIS AG (CH) | 2001-07-25 | — | — | EP | disclosed |
| CN-1039324-C | Substituted azacyclo-pyrimidine compounds, their pharmaceutical salts or N-oxides, and their use as anti-inflammatory agents | AMERICAN HOME PROD (US) | 1998-07-29 | — | — | CN | disclosed |
| CN-1175414-A | Method for preparing substd. azacyclopyrimidine compound, its pharmaceutic salt or N-oxide | AMERICAN HOME PROD (US) | 1998-03-11 | — | — | CN | disclosed |
| EP-0788487-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLES | Novartis AG (CH) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013489-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLES | NOVARTIS AG (CH) | 1996-05-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070290199-A1 | Multi-Functional Copolymers Comprising Rare Earth Metal Complexes and Devices Thereof | ZRANB2, BAZ1A, BAZ2B | ALDH1A1 1961/4885NPSR1 2553/4885NOTUM 3938/4885 |
| US-20100173899-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | F11, TFPI, SERPINC1 | ALDH1A1 4454/4885NPSR1 1815/4885NOTUM 1525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.