Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.62 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.62 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.62 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.43 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | TPI1 | P60174 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182837 | 0.95 | LPAR3 (0.58) | LPAR3LPAR2LPAR1ITPR3ITPR1 | |
| SCHEMBL4534097 | 0.93 | LPAR3 (0.61) | LPAR3LPAR2LPAR1ITPR3ITPR1 | |
| SCHEMBL4536780 | 0.93 | LPAR3 (0.61) | LPAR3LPAR2LPAR1ITPR3ITPR1 | |
| Phosphoric Acid SCHEMBL11284267 | 0.93 | LPAR3 (0.56) | LPAR3LPAR2LPAR1ITPR3ITPR1 | |
| SCHEMBL5575581 | 0.93 | LPAR3 (0.61) | LPAR3LPAR2LPAR1ITPR3ITPR1 | |
| SCHEMBL4538726 | 0.93 | LPAR3 (0.61) | LPAR3LPAR2LPAR1ITPR3ITPR1 | |
| SCHEMBL4519325 | 0.93 | LPAR3 (0.61) | LPAR3LPAR2LPAR1ITPR3ITPR1 | |
| SCHEMBL4537351 | 0.93 | LPAR3 (0.61) | LPAR3LPAR2LPAR1ITPR3ITPR1 | |
| SCHEMBL4535627 | 0.93 | LPAR3 (0.61) | LPAR3LPAR2LPAR1ITPR3ITPR1 | |
| SCHEMBL4529652 | 0.93 | LPAR3 (0.61) | LPAR3LPAR2LPAR1ITPR3ITPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62153952-A | — | — | None | — | — | JP | disclosed |
| WO-2020189201-A1 | METHOD FOR PRODUCING BISPHENOL AND METHOD FOR PRODUCING POLYCARBONATE RESIN | 三菱ケミカル株式会社 | 2020-09-24 | — | — | WO | disclosed |
| US-10265252-B2 | Odor-reducing developer for oxidation dyes | HENKEL AG & CO. KGAA (DE) | 2019-04-23 | — | — | US | disclosed |
| US-20170340531-A1 | ODOR-REDUCING DEVELOPER FOR OXIDATION DYES | HENKEL AG & CO. KGAA (DE) | 2017-11-30 | — | — | US | disclosed |
| EP-2021345-B1 | HYDROXYLATED AMIDE SKIN MOISTURIZER | OREAL (FR) | 2013-07-10 | — | — | EP | disclosed |
| US-20100009931-A1 | ASSOCIATION OF A TENSOR AGENT OR DEVICE AND A SACCHARIDE COMPOUND | L'OREAL (FR) | 2010-01-14 | — | — | US | disclosed |
| US-20070092473-A1 | Cosmetic composition containing a statistical polymer with a linear main chain of ethylenic nature | L'OREAL (FR) | 2007-04-26 | — | — | US | disclosed |
| JP-S62153952-A | DEVELOPMENT PROCESSING METHOD FOR BLACK AND WHITE SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO LTD | 1987-07-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10265252-B2 | Odor-reducing developer for oxidation dyes | HAO2, AOX1, LPO | LPAR3 1194/4885LPAR2 985/4885LPAR1 1135/4885 |
| US-20170340531-A1 | ODOR-REDUCING DEVELOPER FOR OXIDATION DYES | HAO2, AOX1, LPO | LPAR3 1194/4885LPAR2 985/4885LPAR1 1135/4885 |
| US-20100009931-A1 | ASSOCIATION OF A TENSOR AGENT OR DEVICE AND A SACCHARIDE COMPOUND | PIEZO1, TRPA1, TREH | LPAR3 1768/4885LPAR2 1958/4885LPAR1 1622/4885 |
| US-20070092473-A1 | Cosmetic composition containing a statistical polymer with a linear main chain of ethylenic nature | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TELO2, METTL14 | LPAR3 2539/4885LPAR2 3015/4885LPAR1 3106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.