Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | CCR5 | P51681 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265509 | 0.83 | CCR5 (0.41) | CCR5PLATSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3261658 | 0.83 | CCR5 (0.35) | KCNH2CCR5ALDH1A1MEN1KMT2A | |
| SCHEMBL1290745 | 0.83 | SLC6A4 (0.42) | KCNH2L3MBTL1PLATSLC6A4SLC6A2 | |
| SCHEMBL4064287 | 0.76 | PKM (0.43) | CCR5KDM4EOPRM1L3MBTL1 | |
| SCHEMBL967470 | 0.75 | — | — | |
| SCHEMBL967276 | 0.73 | L3MBTL1 (0.49) | MEN1KMT2AL3MBTL1SLC6A4SLC6A2 | |
| SCHEMBL15667928 | 0.73 | SLC6A2 (0.52) | KCNH2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1840824 | 0.73 | SLC6A2 (0.52) | KCNH2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3832363 | 0.73 | ALDH1A1 (0.44) | KCNH2CCR5KDM4EPOLBALDH1A1 | |
| SCHEMBL3959008 | 0.72 | L3MBTL3 (0.41) | KMT2AL3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025073-A1 | DIHYDROIMIDAZO [ 1, 5-F] PTERIDINES AS POLO-LIKE KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | WO | disclosed |