SCHEMBL32675952

SCHEMBL32675952

CCOC(=O)c1ccc(C=O)n1Cc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
ALDH1A1 P00352 6/20 0.53
MAPT P10636 6/20 0.53
POLB P06746 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
ATM Q13315 1/20 0.53
NOD2 Q9HC29 1/20 0.52
NOD1 Q9Y239 1/20 0.52
MAPK1 P28482 1/20 0.51
SMN1; SMN2 Q16637 4/20 0.49
LMNA P02545 6/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
NPSR1 Q6W5P4 3/20 0.47
F10 P00742 2/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 2/20 0.46
PKM P14618 1/20 0.46
HTT P42858 1/20 0.46
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15997499 0.88 TSHR (0.52) TSHRALDH1A1MAPTPOLBTDP1
SCHEMBL23174424 0.87 TSHR (0.62) TSHRALDH1A1MAPTPOLBTDP1
SCHEMBL14858489 0.83 TSHR (0.62) TSHRALDH1A1MAPTPOLBTDP1
SCHEMBL15997500 0.81 TSHR (0.56) TSHRALDH1A1MAPTPOLBTDP1
SCHEMBL32675919 0.80 ALDH1A1 (0.46) TSHRALDH1A1MAPTPOLBTDP1
SCHEMBL9427779 0.80 ACHE (0.44) ALDH1A1MAPTNOD2NOD1LMNA
SCHEMBL9427336 0.77 AGTR1 (0.50) TDP1NOD2NOD1SMN1; SMN2
SCHEMBL31590852 0.77 LMNA (0.46) TSHRALDH1A1POLBSMN1; SMN2LMNA
SCHEMBL32675962 0.77 ALDH1A1 (0.38) TSHRALDH1A1MAPTPOLBTDP1
SCHEMBL23159575 0.76 TP53 (0.41) ALDH1A1MAPTLMNANPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049192-A1 DYED ARTICLES FOR VISIBLE AND INFRARED LIGHT ABSORPTION OAKLEY, INC. (US) 2026-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049192-A1 DYED ARTICLES FOR VISIBLE AND INFRARED LIGHT ABSORPTION CRY1, CRY2, CLIC1 TSHR 1145/4885ALDH1A1 319/4885MAPT 3066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.