SCHEMBL32688043

SCHEMBL32688043

N#Cc1c(-c2ccc(Cl)cc2)nc(=O)[nH]c1SCc1nnn[nH]1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.45
▸ POLB P06746 3/20 0.44
▸ MEN1 O00255 2/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ ACMSD Q8TDX5 1/20 0.43
▸ CXCR2 P25025 2/20 0.43
▸ LDHA P00338 7/20 0.42
▸ ALDH1A1 P00352 1/20 0.39
▸ KDM1A O60341 1/20 0.39
▸ HSD11B1 P28845 2/20 0.38
▸ BRD4 O60885 1/20 0.38
▸ LDHB P07195 2/20 0.38
▸ BLM P54132 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ CA12 O43570 1/20 0.37
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32688268 0.91 MEN1 (0.42) LMNAPOLBMEN1KMT2AACMSD
SCHEMBL32688366 0.90 ACMSD (0.47) POLBMEN1KMT2AACMSDCXCR2
SCHEMBL32688407 0.89 ACMSD (0.39) LMNAPOLBMEN1KMT2AACMSD
SCHEMBL32687967 0.89 MEN1 (0.43) LMNAPOLBMEN1KMT2AACMSD
SCHEMBL32688144 0.88 MEN1 (0.48) LMNAPOLBMEN1KMT2ACXCR2
SCHEMBL32688157 0.88 MEN1 (0.46) POLBMEN1KMT2ACXCR2LDHA
SCHEMBL32688285 0.88 POLB (0.40) LMNAPOLBMEN1KMT2AACMSD
SCHEMBL32688294 0.86 MEN1 (0.41) LMNAPOLBMEN1KMT2AHSD11B1
SCHEMBL32688267 0.84 ADORA1 (0.40) LMNAPOLBMEN1KMT2AACMSD
SCHEMBL32688228 0.83 HSD11B1 (0.40) POLBMEN1KMT2ACXCR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK LMNA 2438/4885POLB 508/4885MEN1 4353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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