SCHEMBL32688407

SCHEMBL32688407

N#Cc1c(-c2ccncc2)nc(=O)[nH]c1SCc1nnn[nH]1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ACMSD Q8TDX5 3/20 0.39
▸ MEN1 O00255 4/20 0.36
▸ KMT2A Q03164 4/20 0.36
▸ POLB P06746 4/20 0.36
▸ CXCR2 P25025 2/20 0.36
▸ BRD4 O60885 1/20 0.36
▸ HSD11B1 P28845 1/20 0.36
▸ ADORA1 P30542 4/20 0.35
▸ ADORA2A P29274 3/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ HPGD P15428 2/20 0.35
▸ TNF P01375 1/20 0.34
▸ PLA2G1B P04054 1/20 0.34
▸ NOD2 Q9HC29 1/20 0.34
▸ NOD1 Q9Y239 1/20 0.34
▸ ATG4B Q9Y4P1 1/20 0.34
▸ ADORA3 P0DMS8 2/20 0.33
▸ LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32688366 0.90 ACMSD (0.47) ACMSDMEN1KMT2APOLBCXCR2
SCHEMBL32688043 0.89 LMNA (0.45) ACMSDMEN1KMT2APOLBCXCR2
SCHEMBL32688268 0.88 MEN1 (0.42) ACMSDMEN1KMT2APOLBCXCR2
SCHEMBL32688267 0.88 ADORA1 (0.40) ACMSDMEN1KMT2APOLBCXCR2
SCHEMBL32688285 0.88 POLB (0.40) ACMSDMEN1KMT2APOLBCXCR2
SCHEMBL32688144 0.86 MEN1 (0.48) MEN1KMT2APOLBCXCR2ADORA1
SCHEMBL32687967 0.85 MEN1 (0.43) ACMSDMEN1KMT2APOLBCXCR2
SCHEMBL32688157 0.84 MEN1 (0.46) MEN1KMT2APOLBCXCR2BRD4
SCHEMBL32688228 0.81 HSD11B1 (0.40) MEN1KMT2APOLBCXCR2BRD4
SCHEMBL32688294 0.80 MEN1 (0.41) MEN1KMT2APOLBHSD11B1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK ACMSD 142/4885MEN1 4353/4885KMT2A 3400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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