SCHEMBL32687967

SCHEMBL32687967

N#Cc1c(-c2ccc(Cl)c(Cl)c2)nc(=O)[nH]c1SCc1nnn[nH]1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.43
▸ KMT2A Q03164 4/20 0.43
▸ CA12 O43570 2/20 0.39
▸ CA1 P00915 2/20 0.39
▸ CA2 P00918 2/20 0.39
▸ CA9 Q16790 2/20 0.39
▸ DCUN1D1 Q96GG9 3/20 0.38
▸ BRD4 O60885 4/20 0.37
▸ CXCR2 P25025 2/20 0.36
▸ HSD11B1 P28845 1/20 0.36
▸ LDHA P00338 1/20 0.35
▸ LDHB P07195 1/20 0.35
▸ IDO1 P14902 1/20 0.35
▸ POLB P06746 3/20 0.35
▸ LMNA P02545 1/20 0.34
▸ ACMSD Q8TDX5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32688043 0.89 LMNA (0.45) MEN1KMT2ACA12CA1CA2
SCHEMBL32688157 0.87 MEN1 (0.46) MEN1KMT2ADCUN1D1BRD4CXCR2
SCHEMBL32688268 0.86 MEN1 (0.42) MEN1KMT2ACA12CA1CA2
SCHEMBL32688366 0.85 ACMSD (0.47) MEN1KMT2ABRD4CXCR2HSD11B1
SCHEMBL32688407 0.85 ACMSD (0.39) MEN1KMT2ABRD4CXCR2HSD11B1
SCHEMBL32688285 0.83 POLB (0.40) MEN1KMT2ACA12CA1CA2
SCHEMBL32688144 0.83 MEN1 (0.48) MEN1KMT2ACA12CA1CA2
SCHEMBL32688294 0.83 MEN1 (0.41) MEN1KMT2ACA12CA2CA9
SCHEMBL32688228 0.83 HSD11B1 (0.40) MEN1KMT2ABRD4CXCR2HSD11B1
SCHEMBL32688267 0.81 ADORA1 (0.40) MEN1KMT2ACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors ORSOBIO INC (US) 2026-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078105-A1 Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors CPT1B, CBR1, MUSK MEN1 4353/4885KMT2A 3400/4885CA12 2559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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