SCHEMBL3271333

SCHEMBL3271333

CC1(c2ccccc2)c2cc(C(=O)O)c(C(=O)O)cc2Oc2cc(C(=O)O)c(C(=O)O)cc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.39
CYP2C9 P11712 2/20 0.38
ALDH1A1 P00352 3/20 0.36
ALOX15 P16050 2/20 0.36
HCAR3 P49019 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
CYP1A2 P05177 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
CASP6 P55212 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 2/20 0.34
CDC25A P30304 1/20 0.34
CDC25B P30305 1/20 0.34
BRD4 O60885 1/20 0.33
CNR1 P21554 1/20 0.33
RARA P10276 1/20 0.33
RARB P10826 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3272803 0.85 TSHR (0.39) ALDH1A1POLBHSD17B10BRD4HPGD
SCHEMBL12804755 0.84 KMT2A (0.45) ALDH1A1CYP1A2MEN1POLBKMT2A
SCHEMBL3274334 0.83 ALOX5 (0.41) ALOX5CYP2C9ALDH1A1ALOX15MEN1
SCHEMBL17238249 0.79 ALOX5 (0.48) ALOX5ALDH1A1HCAR3HCAR2CYP1A2
SCHEMBL3272491 0.79 ALOX5 (0.34) ALOX5CYP2C9ALDH1A1MEN1POLB
SCHEMBL1099586 0.77 PDK2 (0.38) ALOX5CYP2C9ALDH1A1ALOX15MEN1
SCHEMBL9221863 0.76 PDK2 (0.37) ALOX5CYP2C9ALDH1A1ALOX15MEN1
SCHEMBL17914238 0.75 MMP2 (0.41) CYP2C9ALDH1A1ALOX15MMP2MMP9
SCHEMBL9220689 0.75 ALOX5 (0.35) ALOX5CYP2C9ALDH1A1ALOX15MEN1
SCHEMBL9220858 0.75 PDK2 (0.36) ALOX5CYP2C9ALDH1A1ALOX15HCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2092807-B1 COMPOSITE ORGANIC ENCAPSULANTS CDA PROC LTD LIABILITY COMPANY (US) 2013-04-17 EP claimed
US-7745516-B2 Composition of polyimide and sterically-hindered hydrophobic epoxy E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-29 US claimed
US-20090111948-A1 Compositions comprising polyimide and hydrophobic epoxy and phenolic resins, and methods relating thereto CDA PROCESSING LIMITED LIABILITY COMPANY 2009-04-30 US claimed
EP-2027184-A2 HYDROPHOBIC COMPOSITIONS FOR ELECTRONIC APPLICATIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-02-25 EP claimed
US-20080185561-A1 Resistor compositions for electronic circuitry applications U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2008-08-07 US claimed
US-20080185361-A1 Compositions for electronic circuitry applications and methods relating thereto CDA PROCESSING LIMITED LIABILITY COMPANY 2008-08-07 US claimed
EP-1943311-A1 COMPOSITIONS COMPRISING POLYIMIDE AND HYDROPHOBIC EPOXY, AND METHODS RELATING THERETO E.I.Du pont de nemours and company (US) 2008-07-16 EP claimed
WO-2007146382-A2 HYDROPHOBIC COMPOSITIONS FOR ELECTRONIC APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-21 WO claimed
US-20070290379-A1 Hydrophobic compositions for electronic applications E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-20 US claimed
WO-2007047384-A1 COMPOSITIONS COMPRISING POLYIMIDE AND HYDROPHOBIC EPOXY, AND METHODS RELATING THERETO E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-04-26 WO claimed
US-20070083017-A1 Compositions comprising polyimide and hydrophobic epoxy, and methods relating thereto CDA PROCESSING LIMITED LIABILITY COMPANY 2007-04-12 US claimed
US-11760738-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor United States of America as represented by the Adminstrator of NASA (US) 2023-09-19 US disclosed
US-20220017479-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2022-01-20 US disclosed
US-11130742-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2021-09-28 US disclosed
US-10808079-B2 Synthesis of copolyimides containing fluorine and silicon surface modifying agents UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (US) 2020-10-20 US disclosed
US-20070066734-A1 Polycyclic polyimides and compositions and methods relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2007-03-22 US disclosed
EP-1764381-A1 Polycyclic polyimides and compositions and their corresponding polyamic acids E.I.Du pont de nemours and company (US) 2007-03-21 EP disclosed
EP-1749850-A1 Low color polyimide compositions useful in optical type applications and methods and compositions related thereto E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-02-07 EP disclosed
EP-0646406-B1 Polyimide gas separation membranes AIR LIQUIDE (FR) 1998-08-26 EP disclosed
US-5334697-A Contains repeating units derived from 9,9-disubstituted xanthene dianhydride L'AIR LIQUIDE, S.A. (FR) 1994-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760738-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS ALOX5 2145/4885CYP2C9 2003/4885ALDH1A1 3335/4885
US-11130742-B2 Anisotropic copoly(imide oxetane) coatings and articles of manufacture, copoly(imide oxetane)s containing pendant fluorocarbon moieties, oligomers and processes therefor MACF1, OR51E2, FOS ALOX5 2145/4885CYP2C9 2003/4885ALDH1A1 3335/4885
US-20220017479-A1 ANISOTROPIC COPOLY(IMIDE OXETANE) COATINGS AND ARTICLES OF MANUFACTURE, COPOLY(IMIDE OXETANE)S CONTAINING PENDANT FLUOROCARBON MOIETIES, OLIGOMERS AND PROCESSES THEREFOR MACF1, OR51E2, FOS ALOX5 2145/4885CYP2C9 2003/4885ALDH1A1 3335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.