Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526383 | 0.86 | MAPT (0.58) | MAPTHPGDMEN1APAF1USP2 | |
| SCHEMBL1644806 | 0.84 | HPGD (0.50) | MAPTHPGDMEN1APAF1USP2 | |
| Hydrochloric Acid SCHEMBL9181167 | 0.83 | MAPT (0.56) | MAPTHPGDMEN1APAF1USP2 | |
| SCHEMBL19227694 | 0.82 | ADRA2A (0.47) | MAPTHPGDMEN1APAF1USP2 | |
| SCHEMBL12895818 | 0.82 | ADRA2A (0.50) | MAPTHPGDMEN1APAF1USP2 | |
| SCHEMBL8060137 | 0.82 | MEN1 (0.80) | MAPTHPGDMEN1APAF1USP2 | |
| SCHEMBL7052939 | 0.80 | MAPT (0.50) | MAPTHPGDMEN1APAF1USP2 | |
| SCHEMBL3097589 | 0.80 | ADRA2A (0.48) | MAPTHPGDMEN1APAF1USP2 | |
| SCHEMBL7052715 | 0.80 | MAPT (0.45) | MAPTHPGDMEN1APAF1USP2 | |
| SCHEMBL7052718 | 0.80 | ADRA2A (0.48) | MAPTHPGDMEN1APAF1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3773735-B1 | CONJUGATE OF CYTOTOXIC DRUG AND PRODRUG FORM OF SAID CONJUGATE | SYNDIVIA (FR) | 2024-07-10 | — | — | EP | disclosed |
| EP-4122926-A1 | TRIAZINE DERIVATIVE HAVING VIRUS PROPAGATION INHIBITORY EFFECT, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Shionogi & Co., Ltd (JP) | 2023-01-25 | — | — | EP | disclosed |
| CN-107207983-B | Use of a lubricating composition | 国际壳牌研究有限公司 | 2022-11-18 | — | — | CN | disclosed |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| US-11008290-B2 | Halogenated quinoline derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-05-18 | — | — | US | disclosed |
| EP-3483149-B1 | BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | YUHAN CORP (KR) | 2021-01-13 | — | — | EP | disclosed |
| US-10813355-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| WO-2020214336-A2 | SULFUR-HETEROCYCLE EXCHANGE CHEMISTRY AND USES THEREOF | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2020-10-22 | — | — | WO | disclosed |
| US-10752617-B2 | Indazole sulfonamide derivatives as inverse agonists of retinoid-related orphan receptor gamma (ROR gamma (T)) | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2020-08-25 | — | — | US | disclosed |
| US-10752617-B2 | Indazole sulfonamide derivatives as inverse agonists of retinoid-related orphan receptor gamma (ROR gamma (T)) | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2020-08-25 | — | — | US | disclosed |
| EP-0240631-A1 | Alkylation of amines and amides | ETHYL CORPORATION (US) | 1987-10-14 | — | — | EP | disclosed |
| US-4626592-A | WITH A CYCLIC ETHER AND B-SUBGROUP METAL OXIDE ALKYLATION CATALYST | ETHYL CORPORATION (US) | 1986-12-02 | — | — | US | disclosed |
| US-4613705-A | Catalytic alkylation of aromatic amines with alkanols | ETHYL CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| US-4605766-A | REACTING AROMATIC AMINES WITH ETHERS IN PRESENCE OF CATALYST CONTAINING IRON OXIDE | ETHYL CORPORATION (US) | 1986-08-12 | — | — | US | disclosed |
| US-4599449-A | POSSIBLE RECOVERY OF UNUSED ALCOHOL | ETHYL CORPORATION (US) | 1986-07-08 | — | — | US | disclosed |
| EP-0073277-B1 | PROCESS FOR PRODUCING ORTHOALKYLATED AROMATIC AMINES | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1985-07-17 | — | — | EP | disclosed |
| EP-0148009-A2 | Process for the alkylation of aromatic amines and use of the products thereof | ETHYL CORPORATION (US) | 1985-07-10 | — | — | EP | disclosed |
| EP-0073277-A1 | Process for producing orthoalkylated aromatic amines | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1983-03-09 | — | — | EP | disclosed |
| US-4351958-A | Process for producing orthoalkylated aromatic amine | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1982-09-28 | — | — | US | disclosed |
| US-3968188-A | Process for preparing the pentaerythritol ester of phosphorohalidous acid | MONSANTO COMPANY (US) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10813355-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | MAPT 2086/4885HPGD 4292/4885MEN1 1871/4885 |
| US-10752617-B2 | Indazole sulfonamide derivatives as inverse agonists of retinoid-related orphan receptor gamma (ROR gamma (T)) | RORA, RORB, RORC | MAPT 664/4885HPGD 983/4885MEN1 4867/4885 |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | MAPT 1741/4885HPGD 4384/4885MEN1 1675/4885 |
| US-11008290-B2 | Halogenated quinoline derivatives as antimicrobial agents | NDUFS5, NDUFS7, NDUFS3 | MAPT 4764/4885HPGD 1555/4885MEN1 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.