Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16336029 | 0.78 | — | — | |
| SCHEMBL4052700 | 0.78 | DPP4 (0.48) | — | |
| SCHEMBL28484688 | 0.68 | ALPL (0.33) | ALDH1A1TSHR | |
| SCHEMBL5376356 | 0.65 | ALDH1A1 (0.32) | ALDH1A1ALOX15TSHR | |
| SCHEMBL3444433 | 0.64 | ALDH1A1 (0.30) | ALDH1A1ALOX15TSHR | |
| SCHEMBL10617985 | 0.62 | PNP (0.48) | ALDH1A1ALOX15 | |
| SCHEMBL29495248 | 0.62 | NUDT1 (0.39) | — | |
| SCHEMBL37384 | 0.62 | DPP4 (0.66) | ALDH1A1 | |
| SCHEMBL7456301 | 0.62 | — | — | |
| SCHEMBL11456967 | 0.61 | DPP4 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249113-A1 | Fungicidal Mixtures | BASF AKITENGESELLSCHAFT (DE) | 2008-10-09 | — | — | US | claimed |
| CN-1993050-A | Fungicidal synergistic mixtures from triazolopyrimidine derivatives | BASF AG (DE) | 2007-07-04 | — | — | CN | claimed |
| US-20230167121-A1 | SUBSTITUTED {1,2,4,} TRIAZOLO{1,5-A} PYRIMIDINE COMPOUNDS AND USE IN STABILIZING MICROTUBULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-06-01 | — | — | US | disclosed |
| EP-4136089-A1 | SUBSTITUTED {1,2,4,} TRIAZOLO{1,5-A} PYRIMIDINE COMPOUNDS AND USE IN STABILIZING MICROTUBULES | The Trustees of The University of Pennsylvania (US) | 2023-02-22 | — | — | EP | disclosed |
| CN-115397826-A | Substituted {1,2,4, } triazolo {1,5-a } pyrimidine compounds and their use for the stabilization of microtubules | 宾夕法尼亚大学理事会 | 2022-11-25 | — | — | CN | disclosed |
| WO-2021211408-A1 | SUBSTITUTED {1,2,4,} TRIAZOLO{1,5-A} PYRIMIDINE COMPOUNDS AND USE IN STABILIZING MICROTUBULES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2021-10-21 | — | — | WO | disclosed |
| WO-2015162630-A1 | NOVEL PROCESSES FOR PREPARING TRIAZOLO [4,5-D]- PYRIMIDINES, INCLUDING TICAGRELOR, VIANEW INTERMEDIATES AND NEW ROUTE OF SYNTHESIS. | ANLON CHEMICAL RESEARCH ORGANIZATION (IN) | 2015-10-29 | — | — | WO | disclosed |
| WO-2014206187-A1 | PREPARATION METHOD OF TICAGRELOR AND INTERMEDIATES THEREOF | 苏州明锐医药科技有限公司 (CN) | 2014-12-31 | — | — | WO | disclosed |
| US-8372852-B2 | Purines as reverse transcriptase inhibitors | ARDEA BIOSCIENCES, INC. (US) | 2013-02-12 | — | — | US | disclosed |
| US-8372852-B2 | Purines as reverse transcriptase inhibitors | ARDEA BIOSCIENCES, INC. (US) | 2013-02-12 | — | — | US | disclosed |
| US-20120277206-A1 | REVERSE TRANSCRIPTASE INHIBITORS | Andrea Boesciences, Inc. (US) | 2012-11-01 | — | — | US | disclosed |
| CN-1738822-A | Fungicidal triazolopyrimidines, method for the production thereof, use thereof for controlling harmful fungi, and agents containing said fungicidal triazolopyrimidines | BASF AG (DE) | 2006-02-22 | — | — | CN | disclosed |
| US-20060035909-A1 | 2,6,9-trisubstituted 8-azapurines such as 2-(4-aminocyclohexylamino)-6-benzylamino-9-isopropyl-8-azapurine, used as cyclin-dependent kinase inhibitors, in the treatment of skin disorders, viral infections, cancer, arthritis, lupus, diabetes, multiple sclerosis, restenosis, polycystic kidney disease, gout | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2006-02-16 | — | — | US | disclosed |
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |
| EP-0770615-B1 | Process for the preparation of dihaloazolopyrimidines | BASF AG (DE) | 2003-06-18 | — | — | EP | disclosed |
| US-5808066-A | CYCLIZATION REACTION OF 5-AMINO-(1H)-1,2,4-TRIAZOLE WITH MALONIC ACID DIESTER; SALT FORMATION, ACIDIFICATION, HALOGENATION | AMERICAN CYANAMID COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0770615-A1 | Process for the preparation of dihaloazolopyrimidines | American Cyanamid Company (US) | 1997-05-02 | — | — | EP | disclosed |
| EP-0673376-B1 | BICYCLIC PYRIMIDINE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | ADIR (FR) | 1996-05-22 | — | — | EP | disclosed |
| US-5508277-A | Bicyclic pyrimidines | ADIR ET COMPAGNIE (FR) | 1996-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249113-A1 | Fungicidal Mixtures | ARSA, DDT, AZI2 | ALDH1A1 498/4885ALOX15 3271/4885TSHR 2347/4885 |
| US-20230167121-A1 | SUBSTITUTED {1,2,4,} TRIAZOLO{1,5-A} PYRIMIDINE COMPOUNDS AND USE IN STABILIZING MICROTUBULES | MAPT, TUBA4A, MAP4 | ALDH1A1 2113/4885ALOX15 4413/4885TSHR 4078/4885 |
| US-20120277206-A1 | REVERSE TRANSCRIPTASE INHIBITORS | POLRMT, POLR1E, TYMP | ALDH1A1 532/4885ALOX15 1500/4885TSHR 4449/4885 |
| US-20060035909-A1 | 2,6,9-trisubstituted 8-azapurines such as 2-(4-aminocyclohexylamino)-6-benzylamino-9-isopropyl-8-azapurine, used as cyclin-dependent kinase inhibitors, in the treatment of skin disorders, viral infections, cancer, arthritis, lupus, diabetes, multiple sclerosis, restenosis, polycystic kidney disease, gout | CDK8, CDK6, CDK1 | ALDH1A1 2467/4885ALOX15 1017/4885TSHR 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.