Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 4/20 | 0.48 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.47 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260570 | 0.98 | CA1 (0.50) | CA1CA2DNM1GPR84CES2 | |
| SCHEMBL861850 | 0.98 | CA1 (0.50) | CA1CA2DNM1GPR84CES2 | |
| Potassium Ion SCHEMBL29216578 | 0.96 | CA1 (0.46) | CA1CA2DNM1CES2CES1 | |
| SCHEMBL1225942 | 0.83 | CA1 (0.50) | CA1CA2DNM1GPR84CES2 | |
| SCHEMBL1249777 | 0.83 | CA1 (0.50) | CA1CA2DNM1GPR84CES2 | |
| SCHEMBL7500724 | 0.81 | ACE2 (0.44) | DNM1GPR84GGPS1ACE2 | |
| SCHEMBL2175914 | 0.81 | ACE2 (0.44) | DNM1GPR84GGPS1ACE2 | |
| SCHEMBL5495146 | 0.81 | ACE2 (0.44) | DNM1GPR84GGPS1ACE2 | |
| SCHEMBL7500730 | 0.81 | ACE2 (0.44) | DNM1GPR84GGPS1ACE2 | |
| SCHEMBL11442609 | 0.81 | ACE2 (0.44) | DNM1GPR84GGPS1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606685-A | Water-soluble temper rolling liquid composition for non-degreased annealed steel sheet | 大同化学株式会社 | 2023-08-18 | — | — | CN | claimed |
| CN-119174763-A | Composition for inhibiting plaque formation | 盛势达（瑞士）有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-118806618-A | Hair cleansing compositions | 日本乐敦制药株式会社 | 2024-10-22 | — | — | CN | disclosed |
| CN-111201009-B | Hair cleansing compositions | 日本乐敦制药株式会社 | 2024-08-16 | — | — | CN | disclosed |
| CN-113348196-B | Alkylene oxide derivative, antifoaming agent, lubricant, cosmetic base material, and cosmetic and cleaning agent composition containing the same | 日油株式会社 | 2023-09-15 | — | — | CN | disclosed |
| CN-116606685-A | Water-soluble temper rolling liquid composition for non-degreased annealed steel sheet | 大同化学株式会社 | 2023-08-18 | — | — | CN | disclosed |
| US-7700123-B2 | Cosmetics | TECHNOBLE CO., LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20080145905-A1 | COSMETICS | SAWAKI SHIGERU | 2008-06-19 | — | — | US | disclosed |
| EP-1366736-B1 | Use of lactic acid bacteria fermented rice in cosmetics or as emulsifier | TECHNOBLE CO LTD (JP) | 2008-06-11 | — | — | EP | disclosed |
| EP-1366736-A1 | COSMETICS | Technoble Co., Ltd. (JP) | 2003-12-03 | — | — | EP | disclosed |