SCHEMBL328169

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1067002	0.91	CYP19A1 (0.55)	CYP19A1CYP3A4MAPTKMT2AMEN1
	SCHEMBL10512975	0.84	LMNA (0.62)	CYP19A1CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL27910907	0.82	CYP51A1 (0.50)	CYP19A1CYP3A4MAPTKMT2AMEN1
	SCHEMBL5836351	0.82	CYP19A1 (0.48)	CYP19A1CYP3A4MAPTKMT2AMEN1
	SCHEMBL6324609	0.81	L3MBTL1 (0.60)	CYP19A1CYP3A4MAPTMAPK1LMNA
	SCHEMBL10756652	0.80	CYP19A1 (0.56)	CYP19A1CYP3A4MAPTKMT2AMEN1
	SCHEMBL20238568	0.80	HSPB1 (0.56)	HSPB1MAPTKMT2AMEN1NPC1
	SCHEMBL28216870	0.79	ALDH1A1 (0.40)	HSPB1CYP19A1CYP3A4CYP2C9CYP2C19
	SCHEMBL7005980	0.78	CYP3A4 (0.69)	CYP19A1CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL7657342	0.78	CA1 (0.52)	CYP19A1CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.