Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 2/20 | 0.42 |
| ▸ | BMP1 | P13497 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 9/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MMP16 | P51512 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850876 | 0.91 | MMP1 (0.46) | MEP1BBMP1MMP1MMP8MMP13 | |
| SCHEMBL6850859 | 0.91 | SCN9A (0.38) | BMP1SCN9AMMP2CACNA1HCACNA1B | |
| SCHEMBL328402 | 0.90 | MEP1B (0.44) | MEP1BBMP1MMP1MMP8MMP13 | |
| SCHEMBL10067174 | 0.82 | MMP1 (0.54) | MEP1BBMP1MMP1MMP8MMP13 | |
| SCHEMBL328418 | 0.81 | MMP1 (0.45) | MEP1BBMP1MMP1MMP8MMP13 | |
| SCHEMBL328404 | 0.80 | BMP1 (0.43) | MEP1BBMP1MMP1MMP8MMP13 | |
| SCHEMBL328653 | 0.80 | MMP13 (0.46) | MEP1BBMP1MMP1MMP8MMP13 | |
| SCHEMBL6850430 | 0.76 | MMP1 (0.46) | MEP1BBMP1MMP1MMP8MMP13 | |
| SCHEMBL6863608 | 0.72 | MMP1 (0.47) | MEP1BBMP1MMP1MMP8MMP13 | |
| SCHEMBL6864106 | 0.72 | MMP3 (0.50) | MEP1BBMP1MMP1MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428509-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |