Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328417 | 0.91 | MEN1 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6850926 | 0.90 | POLB (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6864106 | 0.82 | MMP3 (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10067175 | 0.82 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL328403 | 0.82 | MEN1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL328406 | 0.81 | MMP3 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6850859 | 0.81 | SCN9A (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6865718 | 0.72 | MMP3 (0.58) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL328410 | 0.72 | MEP1B (0.42) | MMP3SCN9A | |
| SCHEMBL6852266 | 0.71 | HRH3 (0.36) | KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428509-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |