Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3285168

Cc1ccc([S+](c2ccc(C)cc2)c2ccc(C)cc2)cc1.O=C([O-])C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.41
CA2 P00918 1/20 0.40
ALDH1A1 P00352 4/20 0.37
CES2 O00748 3/20 0.37
CES1 P23141 3/20 0.37
LMNA P02545 2/20 0.37
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
HTT P42858 2/20 0.34
KMT2A Q03164 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MEN1 O00255 1/20 0.34
IKBKB O14920 1/20 0.34
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
ATM Q13315 1/20 0.33
NLRP1 Q9C000 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC8 Q9BY41 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL1764860 0.85 ALDH1A1 (0.44) MAPTALDH1A1CES2CES1LMNA
SCHEMBL4962841 0.81 GAA (0.45) MAPTCA2HTTKMT2ANPSR1
Trifluoroacetic Acid SCHEMBL107133 0.79 CES1 (0.45) MAPTCA2CES2CES1TDP1
Trifluoroacetic Acid SCHEMBL11058670 0.78 CA2 (0.41) MAPTCA2ALDH1A1CES2CES1
SCHEMBL4961195 0.77 GAA (0.41) CA2ALDH1A1CES2CES1HTT
SCHEMBL4964156 0.77 GAA (0.41) CA2ALDH1A1CES2CES1HTT
Trifluoroacetic Acid SCHEMBL29564782 0.76 CA2 (0.40) MAPTCA2ALDH1A1CES2CES1
Toliodium SCHEMBL10907987 0.76 CA2 (0.40) MAPTCA2ALDH1A1CES2CES1
Trifluoromethanesulfonic Acid SCHEMBL36224 0.76 GPR3 (0.44) CA2ALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL12762110 0.75 ACHE (0.57) CA2ALDH1A1CES2CES1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7709169-B2 Charge trapping releaser containing charge transport layer photoconductors XEROX CORPORATION (US) 2010-05-04 US claimed
US-7687212-B2 Charge trapping releaser containing photogenerating layer photoconductors XEROX CORPORATION (US) 2010-03-30 US claimed
US-20090092909-A1 CHARGE TRAPPING RELEASER CONTAINING PHOTOGENERATING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-04-09 US claimed
US-20090092908-A1 CHARGE TRAPPING RELEASER CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-04-09 US claimed
US-7709169-B2 Charge trapping releaser containing charge transport layer photoconductors XEROX CORPORATION (US) 2010-05-04 US disclosed
US-7687212-B2 Charge trapping releaser containing photogenerating layer photoconductors XEROX CORPORATION (US) 2010-03-30 US disclosed
US-20090092909-A1 CHARGE TRAPPING RELEASER CONTAINING PHOTOGENERATING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-04-09 US disclosed
US-20090092908-A1 CHARGE TRAPPING RELEASER CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-04-09 US disclosed