SCHEMBL3285175

SCHEMBL3285175

Cc1ccc(S(OC(=O)C(F)(F)F)(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.42
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
GAA P10253 1/20 0.39
NPSR1 Q6W5P4 3/20 0.39
MAPT P10636 2/20 0.39
CA1 P00915 3/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP13 P45452 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
CA5A P35218 2/20 0.36
CA9 Q16790 2/20 0.36
CA12 O43570 1/20 0.36
CA3 P07451 1/20 0.36
CA6 P23280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL361916 0.84 ALDH1A1 (0.47) CA2ALDH1A1MEN1KMT2AGAA
SCHEMBL107134 0.81 CES1 (0.42) ALDH1A1MEN1KMT2AGAAPOLB
SCHEMBL4964247 0.80 CA2 (0.46) CA2ALDH1A1MEN1KMT2AGAA
SCHEMBL756667 0.77 HSD11B1 (0.44) CA2ALDH1A1KMT2AGAANPSR1
SCHEMBL1764861 0.76 LMNA (0.48) CA2ALDH1A1MEN1KMT2AGAA
SCHEMBL4965786 0.76 CA2 (0.42) CA2MEN1KMT2AGAAMAPT
SCHEMBL4961881 0.76 CA2 (0.42) CA2MEN1KMT2AGAAMAPT
Pyridine SCHEMBL28981794 0.74 PTGS2 (0.40) ALDH1A1MEN1KMT2AGAAMAPT
SCHEMBL15286155 0.74 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AGAAMMP1
SCHEMBL9872338 0.71 LMNA (0.57) CA2ALDH1A1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7709169-B2 Charge trapping releaser containing charge transport layer photoconductors XEROX CORPORATION (US) 2010-05-04 US claimed
US-7687212-B2 Charge trapping releaser containing photogenerating layer photoconductors XEROX CORPORATION (US) 2010-03-30 US claimed
US-20090092909-A1 CHARGE TRAPPING RELEASER CONTAINING PHOTOGENERATING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-04-09 US claimed
US-20090092908-A1 CHARGE TRAPPING RELEASER CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-04-09 US claimed
US-7709169-B2 Charge trapping releaser containing charge transport layer photoconductors XEROX CORPORATION (US) 2010-05-04 US disclosed
US-7687212-B2 Charge trapping releaser containing photogenerating layer photoconductors XEROX CORPORATION (US) 2010-03-30 US disclosed
US-20090092909-A1 CHARGE TRAPPING RELEASER CONTAINING PHOTOGENERATING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-04-09 US disclosed
US-20090092908-A1 CHARGE TRAPPING RELEASER CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-04-09 US disclosed