Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28981794 | 0.88 | PTGS2 (0.40) | ALDH1A1GAAMEN1KMT2ALMNA | |
| SCHEMBL28887671 | 0.86 | ALDH1A1 (0.45) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL3285175 | 0.84 | CA2 (0.42) | ALDH1A1GAAMEN1KMT2ACA1 | |
| SCHEMBL9982800 | 0.84 | ALDH1A1 (0.49) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL11047321 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL2227741 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAAF2PRSS1PRSS2 | |
| Ammonia Solution, Strong SCHEMBL2836007 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL15458759 | 0.82 | NPC1 (0.47) | ALDH1A1GAAF2PRSS1PRSS2 | |
| SCHEMBL5900678 | 0.81 | CES1 (0.41) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL1054677 | 0.80 | ALDH1A1 (0.42) | ALDH1A1GAAF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507126-B | Preparation process and application of 6-gingerol | 中国科学院地球化学研究所 | 2023-03-17 | — | — | CN | disclosed |
| CN-114507126-A | Preparation process and application of 6-gingerol | 中国科学院地球化学研究所 | 2022-05-17 | — | — | CN | disclosed |
| US-20180072662-A1 | PROCESS FOR THE MANUFACTURE OF DIHALODIPHENYLSULFONES | SOLVAY SPECIALTY POLYMERS USA, LLC | 2018-03-15 | — | — | US | disclosed |
| US-20180072662-A1 | PROCESS FOR THE MANUFACTURE OF DIHALODIPHENYLSULFONES | SOLVAY SPECIALTY POLYMERS USA, LLC | 2018-03-15 | — | — | US | disclosed |
| US-9850201-B2 | Process for the manufacture of dihalodiphenylsulfones | SOLVAY SPECIALITY POLYMERS USA, LLC (US) | 2017-12-26 | — | — | US | disclosed |
| US-9850201-B2 | Process for the manufacture of dihalodiphenylsulfones | SOLVAY SPECIALITY POLYMERS USA, LLC (US) | 2017-12-26 | — | — | US | disclosed |
| EP-2956455-B1 | IP RECEPTOR AGONIST HETEROCYCLIC COMPOUNDS | NOVARTIS AG (CH) | 2017-05-17 | — | — | EP | disclosed |
| US-9604981-B2 | IP receptor agonist heterocyclic compounds | NOVARTIS AG (CH) | 2017-03-28 | — | — | US | disclosed |
| EP-2593452-B1 | IP RECEPTOR AGONIST HETEROCYCLIC COMPOUNDS | NOVARTIS AG (CH) | 2017-01-18 | — | — | EP | disclosed |
| EP-2699542-B1 | PROCESS FOR THE MANUFACTURE OF DIHALODIPHENYLSULFONES | SOLVAY SPECIALTY POLYMERS USA (US) | 2016-10-12 | — | — | EP | disclosed |
| WO-2011151281-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-12-08 | — | — | WO | disclosed |
| US-7351742-B2 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC. (US) | 2008-04-01 | — | — | US | disclosed |
| EP-1708992-B1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | PFIZER LTD (GB) | 2007-08-08 | — | — | EP | disclosed |
| EP-1708992-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | Pfizer Limited (GB) | 2006-10-11 | — | — | EP | disclosed |
| US-20060128756-A1 | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 2006-06-15 | — | — | US | disclosed |
| WO-2005080324-A1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | PFIZER LIMITED (GB) | 2005-09-01 | — | — | WO | disclosed |
| US-20050171147-A1 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC. | 2005-08-04 | — | — | US | disclosed |
| US-5272265-A | 3-(substituted or unsubstituted) thiazolo-1-carba (1-dethia)cephems | ELI LILLY AND COMPANY (US) | 1993-12-21 | — | — | US | disclosed |
| US-5011825-A | Treatment of hypertension, diabetes, edema | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |
| EP-0194849-A2 | Improved process for producing N-acyl-acyloxy aromatic amines | CELANESE CORPORATION (US) | 1986-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128756-A1 | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses | IL2, IL1A, IL1B | ALDH1A1 871/4885GAA 3028/4885F2 2188/4885 |
| US-20050171147-A1 | Sulfonamide derivatives for the treatment of diseases | SULT2A1, STS, SULT1A1 | ALDH1A1 178/4885GAA 134/4885F2 821/4885 |
| US-20180072662-A1 | PROCESS FOR THE MANUFACTURE OF DIHALODIPHENYLSULFONES | PFAS, DDT, DHPS | ALDH1A1 332/4885GAA 1199/4885F2 2828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.