Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4912147 | 0.81 | METAP1 (0.48) | PGRMETAP1MAPTTDP2CYP19A1 | |
| SCHEMBL4826135 | 0.79 | METAP1 (0.53) | PGRMETAP1MAPTTDP2CYP19A1 | |
| SCHEMBL40823 | 0.79 | METAP1 (0.57) | PGRMETAP1MAPTTDP2CYP19A1 | |
| SCHEMBL28126153 | 0.79 | METAP1 (0.57) | PGRMETAP1MAPTTDP2CYP19A1 | |
| SCHEMBL29376113 | 0.79 | METAP1 (0.57) | PGRMETAP1MAPTTDP2CYP19A1 | |
| SCHEMBL21132350 | 0.79 | PGR (0.49) | PGRHTR2AHTR2CMETAP1MAPT | |
| SCHEMBL3129344 | 0.77 | METAP1 (0.52) | PGRHTR2AHTR2CMETAP1MAPT | |
| SCHEMBL22028099 | 0.77 | CYP3A4 (0.68) | HTR2AHTR2CHTR2BCYP3A4MAPT | |
| SCHEMBL29569917 | 0.77 | METAP1 (0.52) | PGRHTR2AHTR2CMETAP1MAPT | |
| SCHEMBL28360994 | 0.77 | METAP1 (0.52) | PGRHTR2AHTR2CMETAP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838682-B1 | COMPOUNDS THAT ABSORB ULTRAVIOLET LIGHT, METHODS OF THEIR PREPARATION AND OPTICAL LENSES CONTAINING THEM | ESSILOR INT (FR) | 2013-09-25 | — | — | EP | disclosed |
| US-7713452-B2 | Compounds that absorb ultraviolet light, methods of their preparation and optical lenses containing them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2010-05-11 | — | — | US | disclosed |
| US-7713452-B2 | Compounds that absorb ultraviolet light, methods of their preparation and optical lenses containing them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2010-05-11 | — | — | US | disclosed |
| US-7713452-B2 | Compounds that absorb ultraviolet light, methods of their preparation and optical lenses containing them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2010-05-11 | — | — | US | disclosed |
| US-20080064880-A1 | Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D' OPTIQUE (FR) | 2008-03-13 | — | — | US | disclosed |
| US-20080064880-A1 | Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D' OPTIQUE (FR) | 2008-03-13 | — | — | US | disclosed |
| US-20080064880-A1 | Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D' OPTIQUE (FR) | 2008-03-13 | — | — | US | disclosed |
| EP-1838682-A2 | COMPOUNDS THAT ABSORB ULTRAVIOLET LIGHT, METHODS OF THEIR PREPARATION AND OPTICAL LENSES CONTAINING THEM | ESSILOR INTERNATIONAL Compagnie Générale d'Optique (FR) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006069811-A2 | COMPOUNDS THAT ABSORB ULTRAVIOLET LIGHT, METHODS OF THEIR PREPARATION AND OPTICAL LENSES CONTAINING THEM | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2006-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064880-A1 | Compounds That Absorb Ultraviolet Light, Methods of Their Preparation and Optical Lenses Containing Them | CRYAB, CRYAA, CRYZ | PGR 3551/4885HTR2A 4318/4885HTR2C 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.