Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Docusate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Docusate SCHEMBL21634386 | 0.99 | RECQL (0.71) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL17840969 | 0.99 | RECQL (0.71) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL21332902 | 0.93 | RECQL (0.83) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL472563 | 0.92 | RECQL (0.81) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL9775367 | 0.90 | RECQL (0.76) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL11585235 | 0.89 | RECQL (0.78) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL3041223 | 0.89 | RECQL (0.78) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL4113 | 0.89 | RECQL (0.78) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL9722552 | 0.89 | RECQL (0.78) | RECQLCYP3A4TSHRTDP1ATM | |
| SCHEMBL1357097 | 0.89 | RECQL (0.61) | RECQLCYP3A4TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561649-A1 | DRUG-COATED MEDICAL DEVICES AND METHODS OF MAKING | Bard Peripheral Vascular, Inc. (US) | 2025-06-04 | — | — | EP | claimed |
| CN-119486596-A | Solid preparation of insecticidal mixture with excellent dispersion performance | 拜耳公司 | 2025-02-18 | — | — | CN | claimed |
| CN-118973392-A | Water-dispersible granules with low-melting active ingredient prepared by extrusion | 发现号收购集团 | 2024-11-15 | — | — | CN | claimed |
| US-12021262-B2 | Slurry composition including organic particles, sulfosuccinic acid ester, hydrocarbon, and water, adhesive layer formed from the same, separator with adhesive layer, and non-aqueous secondary battery | ZEON CORPORATION (JP) | 2024-06-25 | — | — | US | claimed |
| WO-2024035435-A1 | DRUG-COATED MEDICAL DEVICES AND METHODS OF MAKING | BARD PERIPHERAL VASCULAR, INC. (US) | 2024-02-15 | — | — | WO | claimed |
| US-11831038-B2 | Composition for lithium ion secondary battery separator, two-part composition for lithium ion secondary battery separator, method of producing separator for lithium ion secondary battery, and method of producing lithium ion secondary battery | ZEON CORPORATION (JP) | 2023-11-28 | — | — | US | claimed |
| CN-111902043-B | Solid formulation of insecticidal mixtures | 拜耳公司 | 2023-05-16 | — | — | CN | claimed |
| CN-111935979-B | Solid formulations of insecticide mixtures | 拜耳股份公司 | 2022-12-09 | — | — | CN | claimed |
| EP-4095264-A1 | SURFACE STABILIZATION OF BIOSENSORS | Life Technologies Corporation (US) | 2022-11-30 | — | — | EP | claimed |
| US-11441178-B2 | Surface stabilization of biosensors | Life Technologies Corporation (US) | 2022-09-13 | — | — | US | claimed |
| EP-0843721-A1 | CLEANING AND DISINFECTING COMPOSITIONS WITH ELECTROLYTIC DISINFECTING BOOSTER | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-27 | — | — | EP | claimed |
| EP-0839790-A1 | Antifoulant for acrylic acid purification | NALCO/EXXON ENERGY CHEMICALS, L.P. (US) | 1998-05-06 | — | — | EP | claimed |
| US-5746924-A | SULFONATES | NALCO/EXXON ENERGY CHEMICALS, L.P. (US) | 1998-05-05 | — | — | US | claimed |
| US-5710329-A | SULFONATE | NALCO/EXXON ENERGY CHEMICAL, L. P. (US) | 1998-01-20 | — | — | US | claimed |
| WO-1997006237-A1 | CLEANING AND DISINFECTING COMPOSITIONS WITH ELECTROLYTIC DISINFECTING BOOSTER | THE PROCTER & GAMBLE COMPANY (US) | 1997-02-20 | — | — | WO | claimed |
| CN-1023195-C | Microsuspension process for preparing solvent core sequential polymer dispersion | ROHM & HAAS (US) | 1993-12-22 | — | — | CN | claimed |
| CN-1017339-B | Method for producing fine capsule dispersion | ROHM & HAAS (US) | 1992-07-08 | — | — | CN | claimed |
| CN-1041116-A | Method for producing fine capsule dispersion | ROHM & HAAS (US) | 1990-04-11 | — | — | CN | claimed |
| US-4902824-A | HYDROCARBON SULFONIC ACIDS WITH SOLVENTS OR FATTY ACIDS | NALCO CHEMICAL COMPANY (US) | 1990-02-20 | — | — | US | claimed |
| CN-86103126-A | Method for producing fine capsule dispersion | — | 1986-10-29 | — | — | CN | claimed |