Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346929 | 0.78 | TDP1 (0.41) | — | |
| SCHEMBL346288 | 0.78 | TDP1 (0.41) | — | |
| SCHEMBL28273731 | 0.78 | EP300 (0.46) | EP300MAPTMAPK1TP53CYP1A2 | |
| SCHEMBL28748043 | 0.77 | CYP2D6 (0.35) | EP300MAPTMAPK1TP53CYP1A2 | |
| SCHEMBL22576737 | 0.77 | EP300 (0.44) | EP300FAAHCNR1CNR2 | |
| SCHEMBL27524129 | 0.77 | MAPT (0.43) | MAPTMAPK1PRKCAPRKCEPRKCQ | |
| SCHEMBL3268610 | 0.76 | PRKCA (0.57) | MAPTMAPK1DGKAPRKCAPRKCE | |
| SCHEMBL41614 | 0.76 | PRKCA (0.57) | MAPTMAPK1DGKAPRKCAPRKCE | |
| SCHEMBL27502999 | 0.76 | PRKCA (0.57) | MAPTMAPK1DGKAPRKCAPRKCE | |
| SCHEMBL4230909 | 0.75 | MAPT (0.58) | MAPTMAPK1DGKAPRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3955881-B1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC (US) | 2024-04-24 | — | — | EP | disclosed |
| EP-3898772-B1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2024-03-13 | — | — | EP | disclosed |
| US-11844849-B2 | Dental compositions comprising nanoparticles providing a refractive index differential between polymerizable resin and filler | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-12-19 | — | — | US | disclosed |
| WO-2023239790-A2 | ENHANCING DENTIN BONDING DURABILITY USING QUATERNARY PYRIDINIUM SALTS | ADA Science and Research Institute LLC (US) | 2023-12-14 | — | — | WO | disclosed |
| EP-3529239-B1 | PHOTOINITIATORS WITH PROTECTED CARBONYL GROUP | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-02-15 | — | — | EP | disclosed |
| US-11545614-B2 | Ionic polymer compositions | SABIC GLOBAL TECHNOLOGIES, B.V. (NL) | 2023-01-03 | — | — | US | disclosed |
| EP-4027964-A1 | DENTAL COMPOSITION | Dentsply Sirona Inc. (US) | 2022-07-20 | — | — | EP | disclosed |
| US-20220202658-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2022-06-30 | — | — | US | disclosed |
| US-11319392-B2 | Compositions and methods to antibacterial nanogel and hydrolytically stable antibacterial nanogel for dental compositions | DENTSPLY SIRONA INC. (US) | 2022-05-03 | — | — | US | disclosed |
| US-20220125687-A1 | DENTAL COMPOSITIONS COMPRISING NANOPARTICLES PROVIDING A REFRACTIVE INDEX DIFFERENTIAL BETWEEN POLYMERIZABLE RESIN AND FILLER | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2022-04-28 | — | — | US | disclosed |
| US-20060078831-A1 | Multiphoton curing to provide encapsulated optical elements | 3M INNOVATIVE PROPERTIES COMPANY | 2006-04-13 | — | — | US | disclosed |
| US-7014988-B2 | Multiphoton curing to provide encapsulated optical elements | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-21 | — | — | US | disclosed |
| EP-1578377-A1 | COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS | 3M Innovative Properties Company (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20050208431-A1 | MULTIPHOTON CURING TO PROVIDE ENCAPSULATED OPTICAL ELEMENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2005-09-22 | — | — | US | disclosed |
| WO-2005034884-A1 | DENTAL COMPOSITIONS AND METHODS WITH ARYLSULFINATE SALTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-04-21 | — | — | WO | disclosed |
| US-20050070627-A1 | Dental compositions and methods with arylsulfinate salts | 3M INNOVATIVE PROPERTIES COMPANY | 2005-03-31 | — | — | US | disclosed |
| US-20040206932-A1 | Compositions including polymerizable bisphosphonic acids and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2004-10-21 | — | — | US | disclosed |
| WO-2004060327-A1 | COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-07-22 | — | — | WO | disclosed |
| EP-1295179-A2 | MULTIPHOTON CURING TO PROVIDE ENCAPSULATED OPTICAL ELEMENTS | 3M Innovative Properties Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096917-A2 | MULTIPHOTON CURING TO PROVIDE ENCAPSULATED OPTICAL ELEMENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319392-B2 | Compositions and methods to antibacterial nanogel and hydrolytically stable antibacterial nanogel for dental compositions | RAB5IF, CLPP, PGLS | EP300 983/4885MAPT 2089/4885MAPK1 4077/4885 |
| US-20220202658-A1 | DENTAL COMPOSITION | CAD, PHOSPHO1, PLA2G2C | EP300 478/4885MAPT 2108/4885MAPK1 4323/4885 |
| US-20220125687-A1 | DENTAL COMPOSITIONS COMPRISING NANOPARTICLES PROVIDING A REFRACTIVE INDEX DIFFERENTIAL BETWEEN POLYMERIZABLE RESIN AND FILLER | EPN1, ARCN1, RARA | EP300 1421/4885MAPT 843/4885MAPK1 1739/4885 |
| US-11844849-B2 | Dental compositions comprising nanoparticles providing a refractive index differential between polymerizable resin and filler | EPN1, ARCN1, RARA | EP300 1421/4885MAPT 843/4885MAPK1 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.