Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213083 | 0.89 | HPGD (0.50) | SMN1; SMN2EPHX1EPHX2LMNATP53 | |
| SCHEMBL3300753 | 0.85 | MAPT (0.50) | SMN1; SMN2LMNATP53RAB9ANPC1 | |
| SCHEMBL11201092 | 0.85 | MAPT (0.50) | SMN1; SMN2LMNATP53RAB9ANPC1 | |
| SCHEMBL4820760 | 0.80 | MAPT (0.62) | SMN1; SMN2EPHX1LMNATP53RAB9A | |
| SCHEMBL6352246 | 0.80 | MAPT (0.49) | SMN1; SMN2EPHX1LMNATP53RAB9A | |
| SCHEMBL13769293 | 0.80 | NPY5R (0.47) | SMN1; SMN2LMNATP53RAB9ANPC1 | |
| SCHEMBL29196025 | 0.79 | ESR2 (0.45) | SMN1; SMN2LMNATP53RAB9AALDH1A1 | |
| SCHEMBL3295807 | 0.79 | ALDH1A1 (0.50) | EPHX1EPHX2LMNANFKB1CHEK2 | |
| SCHEMBL11199863 | 0.78 | NPY5R (0.60) | SMN1; SMN2LMNATP53RAB9AHTT | |
| SCHEMBL1335958 | 0.78 | NPY5R (0.60) | SMN1; SMN2LMNATP53RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584753-B2 | Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) | MERCK PATENT GMBH (DE) | 2023-02-21 | — | — | US | disclosed |
| US-20180033965-A1 | NOVEL DIAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) | 2018-02-01 | — | — | US | disclosed |
| EP-1847525-B1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO (JP) | 2010-12-15 | — | — | EP | disclosed |
| US-7834214-B2 | Aromatic amine derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| US-7737628-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-06-15 | — | — | US | disclosed |
| US-20090058284-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| US-7470472-B2 | Aromatic amine derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2008-12-30 | — | — | US | disclosed |
| EP-1847525-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
| EP-1762562-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-20060194074-A1 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2006-08-31 | — | — | US | disclosed |
| US-20060177693-A1 | Aromatic amine derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180033965-A1 | NOVEL DIAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | OR10J3, AOC1, SAT1 | SMN1; SMN2 2724/4885EPHX1 2251/4885EPHX2 2048/4885 |
| US-20090058284-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | TYR, DDC, MAOA | SMN1; SMN2 1959/4885EPHX1 547/4885EPHX2 379/4885 |
| US-11584753-B2 | Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) | OCIAD1, OCIAD2, AOC1 | SMN1; SMN2 3508/4885EPHX1 271/4885EPHX2 177/4885 |
| US-20060194074-A1 | Aromatic amine derivative and organic electroluminescence device using the same | TYR, DDC, AOC2 | SMN1; SMN2 2191/4885EPHX1 531/4885EPHX2 380/4885 |
| US-20060177693-A1 | Aromatic amine derivative and organic electroluminescence device employing the same | TYR, DDC, MAOA | SMN1; SMN2 1959/4885EPHX1 547/4885EPHX2 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.