SCHEMBL816045

SCHEMBL816045

CC(C)(C)c1c[c]nc(C(C)(C)C)c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3296352 0.85 KIF11 (0.31)
SCHEMBL3290373 0.85 GABRA2 (0.35) GABRB2
SCHEMBL3292713 0.77 POLB (0.33) TSHRGABRA1GABRB2
SCHEMBL3289818 0.77 TSHR (0.32) TSHR
SCHEMBL3296403 0.72
SCHEMBL3290129 0.72
SCHEMBL3290084 0.72 HMGCR (0.32)
SCHEMBL3292833 0.72
SCHEMBL3289383 0.71
SCHEMBL3289169 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10144791-B2 Molecular weight control of polyolefins using halogenated bis-phenylphenoxy catalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-04 US claimed
US-20170158790-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC 2017-06-08 US claimed
EP-3925989-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS Dow Global Technologies LLC (US) 2021-12-22 EP disclosed
US-10836697-B2 Process for the preparation of lightly-branched hydrophobes and the corresponding surfactants and applications thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2020-11-17 US disclosed
EP-2797963-B1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-03 EP disclosed
US-20190112250-A1 PROCESS FOR THE PREPARATION OF LIGHTLY-BRANCHED HYDROPHOBES AND THE CORRESPONDING SURFACTANTS AND APPLICATIONS THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-18 US disclosed
US-10196336-B2 Process for the preparation of lightly-branched hydrophobes and the corresponding surfactants and applications thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2019-02-05 US disclosed
EP-2986586-B1 PROCESS FOR THE PREPARATION OF A LIGHTLY-BRANCHED HYDROPHOBE AND THE CORRESPONDING SURFACTANTS AND APPLICATIONS THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2018-08-08 EP disclosed
US-9963648-B2 Process for the preparation of branched polyolefins for lubricant applications DOW GLOBAL TECHNOLOGIES LLC (US) 2018-05-08 US disclosed
EP-3013926-B1 PROCESS FOR THE PREPARATION OF BRANCHED POLYOLEFINS FOR LUBRICANT APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-12-27 EP disclosed
US-9605098-B2 Molecular weight control of polyolefins using halogenated bis-phenylphenoxy catalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-28 US disclosed
US-20140357918-A1 PROCESS FOR PRODUCING LOW MOLECULAR WEIGHT ETHYLENE- AND ALPHA-OLEFIN-BASED MATERIALS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-04 US disclosed
US-20140330056-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-06 US disclosed
US-20140163186-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2014-06-12 US disclosed
US-8609794-B2 Process for selectively polymerizing ethylene and catalyst therefor DOW GLOBAL TECHNOLOGIES, LLC. (US) 2013-12-17 US disclosed
EP-2491062-B1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-11 EP disclosed
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC 2011-11-17 US disclosed
US-7723384-B2 Keto lactam compounds and use thereof ABBOTT GMBH & CO. KG. (DE) 2010-05-25 US disclosed
EP-1692129-B1 KETO LACTAM COMPOUNDS AND USE THEREOF ABBOTT GMBH & CO KG (DE) 2008-08-20 EP disclosed
US-20070219182-A1 Keto Lactam Compounds and Use Thereof ABBVIE DEUTSCHLAND GMBH & CO KG (DE) 2007-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10836697-B2 Process for the preparation of lightly-branched hydrophobes and the corresponding surfactants and applications thereof ERG28, CLTB, CHN2 TSHR 4749/4885GABRA1 779/4885GABRB2 725/4885
US-20140357918-A1 PROCESS FOR PRODUCING LOW MOLECULAR WEIGHT ETHYLENE- AND ALPHA-OLEFIN-BASED MATERIALS EEF1D, EPN1, ELOC TSHR 4824/4885GABRA1 4455/4885GABRB2 4384/4885
US-10196336-B2 Process for the preparation of lightly-branched hydrophobes and the corresponding surfactants and applications thereof ERG28, CLTB, CHN2 TSHR 4749/4885GABRA1 779/4885GABRB2 725/4885
US-20110282018-A1 PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR WEE2, NOTUM, WEE1 TSHR 4494/4885GABRA1 1877/4885GABRB2 2726/4885
US-20190112250-A1 PROCESS FOR THE PREPARATION OF LIGHTLY-BRANCHED HYDROPHOBES AND THE CORRESPONDING SURFACTANTS AND APPLICATIONS THEREOF ERG28, CLTB, CHN2 TSHR 4735/4885GABRA1 818/4885GABRB2 716/4885
US-20070219182-A1 Keto Lactam Compounds and Use Thereof OPRD1, DRD3, OPRK1 TSHR 236/4885GABRA1 390/4885GABRB2 376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.