SCHEMBL3298337

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4756390	0.94	SMN1; SMN2 (0.45)	MAPTALDH1A1KDM4ELMNATP53
	SCHEMBL3305367	0.88	SMN1; SMN2 (0.49)	MAPTALDH1A1KDM4ELMNATP53
	SCHEMBL10059737	0.83	HTR3E (0.44)	MAPTALDH1A1KDM4EHPGDHSD17B10
	SCHEMBL3304455	0.80	ALDH1A1 (0.54)	MAPTALDH1A1KDM4ELMNAHPGD
	SCHEMBL758900	0.76	ALDH1A1 (0.62)	MAPTALDH1A1KDM4ELMNAHPGD
	SCHEMBL3305184	0.76	ALDH1A1 (0.58)	MAPTALDH1A1KDM4ELMNAHPGD
	SCHEMBL3301674	0.75	ALDH1A1 (0.62)	MAPTALDH1A1KDM4ELMNATP53
	SCHEMBL3302437	0.75	KDM4E (0.53)	MAPTALDH1A1KDM4ELMNAHPGD
	SCHEMBL10059452	0.74	ALDH1A1 (0.51)	MAPTALDH1A1KDM4EHPGDHSD17B10
	SCHEMBL3307189	0.73	ALDH1A1 (0.46)	MAPTALDH1A1KDM4EHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.