SCHEMBL3305367

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4756390	0.94	SMN1; SMN2 (0.45)	SMN1; SMN2TSHRLMNAMAPTHTT
	SCHEMBL3298337	0.88	MAPT (0.48)	SMN1; SMN2TSHRLMNAMAPTHTT
	SCHEMBL10059737	0.86	HTR3E (0.44)	SMN1; SMN2MAPTHSD17B10KDM4EALDH1A1
	SCHEMBL3304455	0.80	ALDH1A1 (0.54)	LMNAMAPTHTTGAAHSD17B10
	SCHEMBL758900	0.76	ALDH1A1 (0.62)	SMN1; SMN2LMNAMAPTHTTGAA
	SCHEMBL3305184	0.76	ALDH1A1 (0.58)	LMNAMAPTHTTGAAHSD17B10
	SCHEMBL3301674	0.75	ALDH1A1 (0.62)	TSHRLMNAMAPTGAAHSD17B10
	SCHEMBL3307189	0.73	ALDH1A1 (0.46)	TSHRMAPTHTTGAAHSD17B10
	SCHEMBL3302437	0.72	KDM4E (0.53)	SMN1; SMN2LMNAMAPTGAAHSD17B10
	SCHEMBL10079100	0.72	ALDH1A1 (0.53)	LMNAMAPTHTTHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.