SCHEMBL3299885

SCHEMBL3299885

CN1CCN(CCS)CC1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.40
MC4R P32245 1/20 0.38
SIGMAR1 Q99720 4/20 0.38
KDM4E B2RXH2 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
GAA P10253 1/20 0.36
ALOX15 P16050 1/20 0.36
LMNA P02545 1/20 0.35
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
CSNK2A1 P68400 1/20 0.35
CSNK2A3 Q8NEV1 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
TMEM97 Q5BJF2 1/20 0.35
MGLL Q99685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9386587 0.97 PAOX (0.39) PAOXMC4RSIGMAR1KDM4ETDP1
SCHEMBL10829091 0.87 ALOX15 (0.44) KDM4EALOX15
SCHEMBL8775141 0.87
SCHEMBL1673059 0.87 ALOX15 (0.44) KDM4EALOX15
SCHEMBL9277448 0.83 PAOX (0.47) PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1
SCHEMBL27923832 0.81 PAOX (0.50) PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1
SCHEMBL6143515 0.81 PAOX (0.46) PAOXMC4RSIGMAR1ALOX15LMNA
SCHEMBL40839 0.81 PAOX (0.46) PAOXMC4RSIGMAR1ALOX15LMNA
SCHEMBL15183069 0.80 SIGMAR1 (0.37) SIGMAR1KDM4EGAAALOX15
SCHEMBL686085 0.80 DRD2 (0.43) SIGMAR1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823069-A Inhibitor for improving rheumatoid arthritis by targeting C3aR1 and application thereof 安徽省立医院(中国科学技术大学附属第一医院) 2025-04-15 CN claimed
CN-103153329-A Use of novel cyclosporin A derivatives for the treatment and prevention of viral infections S & T GLOBAL INC 2013-06-12 CN claimed
EP-0614664-B2 Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-01-08 EP claimed
EP-0614664-B1 Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-09-16 EP claimed
US-5519024-A CELL ADHESION INHIBITOR TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-05-21 US claimed
US-5304647-A Addition of an organolithium reagent; dehydrogenation of addition product; two-phase conditions prevents hydrolysis GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) 1994-04-19 US claimed
WO-1989011279-A1 NUCLEIC ACID INTERACTING UNFUSED HETEROPOLYCYCLIC COMPOUNDS GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) 1989-11-30 WO claimed
WO-1989007599-A2 NOVEL DIAZINES AND THEIR METHOD OF PREPARATION GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) 1989-08-24 WO claimed
CN-119823069-A Inhibitor for improving rheumatoid arthritis by targeting C3aR1 and application thereof 安徽省立医院(中国科学技术大学附属第一医院) 2025-04-15 CN disclosed
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2023-11-02 US disclosed
EP-4219516-A2 CHIRAL CONTROL Wave Life Sciences Ltd. (SG) 2023-08-02 EP disclosed
EP-4137572-A1 CHIRAL DESIGN Wave Life Sciences Ltd. (SG) 2023-02-22 EP disclosed
EP-2872147-B1 METHOD FOR MAKING CHIRAL OLIGONUCLEOTIDES WAVE LIFE SCIENCES LTD (SG) 2022-12-21 EP disclosed
US-10647747-B2 Cyclosporin derivatives and uses thereof S&T GLOBAL INC. (US) 2020-05-12 US disclosed
US-4590004-A MICROBIOCIDES RHONE-POULENC SANTE (FR) 1986-05-20 US disclosed
EP-0074599-A1 5,6-cis-Carbapenem derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1983-03-23 EP disclosed
US-4278674-A ANTIBACTERIAL ANTIBIOTICS SANDOZ LTD. (CH) 1981-07-14 US disclosed
US-4208326-A ANTIBIOTICS SANDOZ LTD. (CH) 1980-06-17 US disclosed
US-4107164-A ANTIBIOTICS, ANTIBACTERIAL SANDOZ LTD. (CH) 1978-08-15 US disclosed
US-4032530-A ANTIBIOTICS SANDOZ LTD. (CH) 1977-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647747-B2 Cyclosporin derivatives and uses thereof FKBP5, FKBP1B, MALT1 PAOX 3995/4885MC4R 679/4885SIGMAR1 4049/4885
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION POLRMT, DCLRE1B, RNGTT PAOX 1226/4885MC4R 1568/4885SIGMAR1 4094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.