Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | CASP7 | P55210 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590334 | 0.87 | CA2 (0.40) | CA12CA1CA2CA3CA4 | |
| SCHEMBL29510768 | 0.80 | ADRA2A (0.53) | CA12CA1CA2CA3CA4 | |
| SCHEMBL3313702 | 0.80 | ADRA2A (0.53) | CA12CA1CA2CA3CA4 | |
| Water SCHEMBL7373734 | 0.78 | ADRA2A (0.52) | CA12CA1CA2CA3CA4 | |
| SCHEMBL13395713 | 0.76 | TSHR (0.47) | CA12CA1CA2CA3CA4 | |
| Ethylene Glycol SCHEMBL29225457 | 0.76 | ADRA2A (0.50) | CA12CA1CA2CA3CA4 | |
| SCHEMBL17774539 | 0.74 | ALDH1A1 (0.54) | CA12CA1CA2CA3CA4 | |
| SCHEMBL2138202 | 0.73 | ALDH1A1 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19455779 | 0.72 | CISD1 (0.42) | CA12CA1CA2CA3CA4 | |
| SCHEMBL3675267 | 0.72 | KMT2A (0.54) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105755-A1 | SUBSTITUTED BENZAMIDE MODULATORS OF DOPAMINE RECEPTOR | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-04-29 | — | — | US | disclosed |
| US-20100105755-A1 | SUBSTITUTED BENZAMIDE MODULATORS OF DOPAMINE RECEPTOR | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-04-29 | — | — | US | disclosed |
| US-20100105755-A1 | SUBSTITUTED BENZAMIDE MODULATORS OF DOPAMINE RECEPTOR | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105755-A1 | SUBSTITUTED BENZAMIDE MODULATORS OF DOPAMINE RECEPTOR | DBH, SLC6A3, HTR5A | CA12 4370/4885CA1 4135/4885CA2 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.