Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22680921 | 0.82 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL9846342 | 0.80 | ALDH1A1 (0.34) | ALDH1A1TSHR | |
| SCHEMBL3310787 | 0.77 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL11678374 | 0.76 | CHRM1 (0.38) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3254074 | 0.76 | LMNA (0.34) | ALDH1A1TSHR | |
| SCHEMBL9792595 | 0.75 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL6672411 | 0.74 | LMNA (0.33) | ALDH1A1 | |
| SCHEMBL9624015 | 0.73 | DNM1 (0.43) | ALDH1A1TSHR | |
| SCHEMBL14674 | 0.69 | — | — | |
| SCHEMBL3316208 | 0.69 | ALDH1A1 (0.35) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318160-B1 | Catalysts and process for the preparation of isocyanurate group containing polyisocyanates and their use | DEGUSSA (DE) | 2007-09-26 | — | — | EP | claimed |
| EP-1318152-B1 | Catalysts and process for preparing polyisocyanates containing isocyanurate groups | DEGUSSA (DE) | 2007-09-19 | — | — | EP | claimed |
| US-6875243-B2 | Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use | DEGUSSA AG (DE) | 2005-04-05 | — | — | US | claimed |
| US-20030135007-A1 | Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use | DEGUSSA AG (DE) | 2003-07-17 | — | — | US | claimed |
| US-20030109665-A1 | Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use | DEGUSSA AG (DE) | 2003-06-12 | — | — | US | claimed |
| US-4412073-A | Isocyanurate preparation by catalytic, aminosilyl initiated cyclotrimerization of isocyanates | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-10-25 | — | — | US | claimed |
| US-8445622-B2 | Process for preparing polyisocyanates | BASF SE (DE) | 2013-05-21 | — | — | US | disclosed |
| US-20100292396-A1 | PROCESS FOR PREPARING POLYISOCYANATES | BASF SE (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100105833-A1 | WATER-EMULSIFIABLE POLYISOCYANATES | BASF SE (DE) | 2010-04-29 | — | — | US | disclosed |
| US-6875243-B2 | Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use | DEGUSSA AG (DE) | 2005-04-05 | — | — | US | disclosed |
| US-20030135007-A1 | Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use | DEGUSSA AG (DE) | 2003-07-17 | — | — | US | disclosed |
| US-20030109665-A1 | Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use | DEGUSSA AG (DE) | 2003-06-12 | — | — | US | disclosed |
| US-4697014-A | Catalytic partial cyclotrimerization of polyisocyanates and product thereof | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-09-29 | — | — | US | disclosed |
| US-4675401-A | Process for preparing polyisocyanato/polyisocyanurates by catalytic cyclotrimerization of polyisocyanates | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-06-23 | — | — | US | disclosed |
| US-4537961-A | Catalytic cyclotrimerization of polyisocyanates | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-08-27 | — | — | US | disclosed |
| US-4412073-A | Isocyanurate preparation by catalytic, aminosilyl initiated cyclotrimerization of isocyanates | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292396-A1 | PROCESS FOR PREPARING POLYISOCYANATES | PCBP1, ALKBH3, AGPS | ALDH1A1 2951/4885TSHR 4847/4885MLYCD 496/4885 |
| US-20100105833-A1 | WATER-EMULSIFIABLE POLYISOCYANATES | AQP3, AQP1, AQP4 | ALDH1A1 2387/4885TSHR 4807/4885MLYCD 1988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.