Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18555614 | 1.00 | LMNA (0.39) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL13532069 | 1.00 | LMNA (0.39) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL104210 | 0.97 | — | — | |
| SCHEMBL95613 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL1551987 | 0.86 | — | — | |
| SCHEMBL754871 | 0.86 | HRH4 (0.45) | ALDH1A1HRH4HRH3KDM4EADRB2 | |
| SCHEMBL2479475 | 0.86 | HRH4 (0.45) | ALDH1A1HRH4HRH3KDM4EADRB2 | |
| SCHEMBL841330 | 0.86 | HRH4 (0.45) | ALDH1A1HRH4HRH3KDM4EADRB2 | |
| SCHEMBL4789143 | 0.86 | HRH4 (0.45) | ALDH1A1HRH4HRH3KDM4EADRB2 | |
| SCHEMBL19350614 | 0.86 | HRH4 (0.45) | ALDH1A1HRH4HRH3KDM4EADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11672818-B2 | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-06-13 | — | — | US | disclosed |
| US-20230174679-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2023-06-08 | — | — | US | disclosed |
| US-20220127247-A1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS INSTITUTE FOR FUNCTIONAL GENOMICS, INC., DBA THE GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION (GNF) | 2022-04-28 | — | — | US | disclosed |
| EP-3921313-A1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | Novartis AG (CH) | 2021-12-15 | — | — | EP | disclosed |
| CN-113423702-A | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use in the treatment of disease | 诺华股份有限公司 | 2021-09-21 | — | — | CN | disclosed |
| US-20210147385-A1 | COMPOUNDS AND METHODS FOR TARGETING PATHOGENIC BLOOD VESSELS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-05-20 | — | — | US | disclosed |
| WO-2020161623-A1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2020-08-13 | — | — | WO | disclosed |
| US-9708628-B2 | Cationic lipid having improved intracellular kinetics | NOF CORPORATION (JP) | 2017-07-18 | — | — | US | disclosed |
| US-20160151335-A1 | METHODS OF MODULATING CFTR ACTIVITY | PROTEOSTASIS THERAPEUTICS, INC. (US) | 2016-06-02 | — | — | US | disclosed |
| EP-2694470-B1 | EPOXYEICOSATRIENOIC ACID ANALOGS AND METHODS OF MAKING AND USING THE SAME | WISCONSIN MED COLLEGE INC (US) | 2016-06-01 | — | — | EP | disclosed |
| US-4212734-A | Inhibiting scale with amino-phosphonic-sulfonic acids | PETROLITE CORPORATION (US) | 1980-07-15 | — | — | US | disclosed |
| US-4206233-A | Microbiocidal quaternaries of halogen derivatives of alkynoxymethyl amines | PETROLITE CORPORATION (US) | 1980-06-03 | — | — | US | disclosed |
| US-4187245-A | ANTISCALING AGENTS, CORROSION INHIBITORS, RUST CLEANERS, CHELATION AGENTS | PETROLITE CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
| US-4187277-A | Process of inhibiting corrosion with quaternaries of halogen derivatives of alkynoxymethyl amines | PETROLITE CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
| US-4120654-A | Alkynoxymethyl amines as corrosion inhibitors | PETROLITE CORPORATION (US) | 1978-10-17 | — | — | US | disclosed |
| US-4101674-A | Halogen derivatives of alkynoxymethyl amines as microbiocides | PETROLITE CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4085134-A | ANTISCALING, CORROSION RESISTANCE, CHELATING AGENTS | PETROLITE CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-4065260-A | Halogen derivatives of alkynoxymethyl amines as corrosion inhibitors | PETROLITE CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4026946-A | CORROSION INHIBITORS | PETROLITE CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |
| US-4026807-A | CORROSION INHIBITORS | PETROLITE CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174679-A1 | NITRIC OXIDE-RELEASING ANTIBACTERIAL POLYMERS AND SCAFFOLDS FABRICATED THEREFROM AND METHODS PERTAINING THERETO | NOS2, NOS3, NOS1 | LMNA 2073/4885ALDH1A1 753/4885HSD17B10 2013/4885 |
| US-20160151335-A1 | METHODS OF MODULATING CFTR ACTIVITY | CFTR, HSP90B1, SERPINB1 | LMNA 2112/4885ALDH1A1 2611/4885HSD17B10 2263/4885 |
| US-11672818-B2 | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto | NOS1, NOS2, NOS3 | LMNA 3685/4885ALDH1A1 2342/4885HSD17B10 1173/4885 |
| US-20220127247-A1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | CFTR, P2RY1, P2RX5 | LMNA 2487/4885ALDH1A1 1455/4885HSD17B10 4210/4885 |
| US-20210147385-A1 | COMPOUNDS AND METHODS FOR TARGETING PATHOGENIC BLOOD VESSELS | TEK, KDR, LIPG | LMNA 757/4885ALDH1A1 3295/4885HSD17B10 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.