Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CD38 | P28907 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 4/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3316449 | 0.87 | AAK1 (0.47) | CD38UBE2MDCUN1D1MEN1KMT2A | |
| SCHEMBL4920592 | 0.83 | MAPT (0.42) | TP53LMNAUBE2MDCUN1D1MEN1 | |
| SCHEMBL4359232 | 0.81 | ACHE (0.39) | TP53LMNAUBE2MDCUN1D1MEN1 | |
| SCHEMBL4351294 | 0.80 | ALDH1A1 (0.39) | TP53LMNAUBE2MDCUN1D1MEN1 | |
| SCHEMBL4354386 | 0.74 | CCR2 (0.41) | TP53LMNAUBE2MDCUN1D1MEN1 | |
| SCHEMBL3314880 | 0.72 | NAMPT (0.57) | BLMLMNAROCK1MEN1KMT2A | |
| SCHEMBL4345577 | 0.72 | HDAC3 (0.36) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL11027292 | 0.72 | MST1R (0.43) | UBE2MDCUN1D1 | |
| SCHEMBL4359597 | 0.72 | LMNA (0.42) | LMNAUBE2MDCUN1D1MEN1KMT2A | |
| SCHEMBL4347969 | 0.72 | EGFR (0.43) | TP53LMNAUBE2MDCUN1D1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105904-A1 | UREA TYPE CINNAMIDE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-04-29 | — | — | US | disclosed |
| EP-2019093-A1 | UREA TYPE CINNAMIDE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105904-A1 | UREA TYPE CINNAMIDE DERIVATIVE | SLC14A1, UTS2R, MAN2B1 | BLM 4392/4885CD38 1427/4885TP53 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.