SCHEMBL3316449

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3318296	0.87	BLM (0.43)	HTTMEN1KMT2AUBE2MDCUN1D1
	SCHEMBL4449706	0.73	AAK1 (0.65)	AAK1CYP19A1CYP11B1CYP11B2HTT
	SCHEMBL4920592	0.72	MAPT (0.42)	HTTSMN1; SMN2MEN1KMT2AALDH1A1
	SCHEMBL4354386	0.72	CCR2 (0.41)	MEN1KMT2AALDH1A1MAPTUBE2M
	SCHEMBL4359232	0.72	ACHE (0.39)	TSHRSMN1; SMN2MEN1KMT2AALDH1A1
	SCHEMBL3316441	0.72	KMT2A (0.56)	AAK1TSHRHTTSMN1; SMN2MEN1
	SCHEMBL5649471	0.72	CCNT1 (0.52)	ALOX15TSHRALDH1A1
	SCHEMBL4351294	0.71	ALDH1A1 (0.39)	SMN1; SMN2MEN1KMT2AALDH1A1MAPT
	SCHEMBL4359597	0.70	LMNA (0.42)	HTTSMN1; SMN2MEN1KMT2AALDH1A1
	SCHEMBL4347969	0.70	EGFR (0.43)	MEN1KMT2AALDH1A1MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.