SCHEMBL901069

SCHEMBL901069

O=C(O)c1ccc(C(=O)O)c(-c2ccc(-c3ccccc3)cc2)c1-c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 3/20 0.61
HNF4A P41235 3/20 0.61
DHFR P00374 1/20 0.55
MCL1 Q07820 1/20 0.55
CDC25B P30305 1/20 0.55
ATM Q13315 1/20 0.55
DCLRE1A Q6PJP8 1/20 0.53
DCLRE1B Q9H816 1/20 0.53
ALDH1A1 P00352 2/20 0.52
ALOX15 P16050 1/20 0.52
WDR5 P61964 1/20 0.52
MAPT P10636 2/20 0.48
DHODH Q02127 1/20 0.47
PTPN1 P18031 2/20 0.47
KDM4E B2RXH2 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
ACLY P53396 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL332581 0.95 ALDH1A1 (0.57) ACMSDHNF4ADHFRMCL1CDC25B
SCHEMBL28391136 0.88 HNF4A (0.59) ACMSDHNF4ADHFRMCL1CDC25B
SCHEMBL8422568 0.87 CYP3A4 (0.54) ACMSDHNF4ADHFRMCL1CDC25B
SCHEMBL9756514 0.85 WDR5 (0.47) ACMSDHNF4ADHFRMCL1CDC25B
SCHEMBL12006684 0.85 HNF4A (0.55) ACMSDHNF4ADHFRMCL1CDC25B
SCHEMBL9152464 0.85 ACMSD (0.55) ACMSDHNF4ADHFRMCL1ALDH1A1
SCHEMBL27734925 0.84 CDC25B (0.50) ACMSDHNF4ACDC25BATMALDH1A1
SCHEMBL70098 0.83 HNF4A (0.63) ACMSDHNF4ACDC25BATMALDH1A1
Salicylic Acid SCHEMBL5703937 0.83 ALDH1A1 (0.72) ACMSDHNF4ADHFRMCL1CDC25B
SCHEMBL5820920 0.83 FABP3 (0.54) ACMSDHNF4AALDH1A1ALOX15WDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573573-B1 MESOGENIC GLYCIDYL AMINES DOW CHEMICAL CO (US) 1999-09-29 EP claimed
US-5391651-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1995-02-21 US claimed
EP-0573573-A1 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1993-12-15 EP claimed
US-5270405-A Mesogenic epoxy compounds THE DOW CHEMICAL COMPANY (US) 1993-12-14 US claimed
US-5270404-A Curable compositions of mesogen-containing advanced epoxy resins and curing agents therefor THE DOW CHEMICAL COMPANY (US) 1993-12-14 US claimed
US-5248740-A Thioepoxides, liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1993-09-28 US claimed
US-5218062-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1993-06-08 US claimed
US-5182340-A Molding materials having shorter gel time with aliphatic amine curing agents THE DOW CHEMICAL COMPANY (US) 1993-01-26 US claimed
WO-1992015630-A2 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO claimed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP claimed
EP-0473935-A2 Curable mixture of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP claimed
US-9340702-B2 Coating compositions BLUE CUBE IP LLC (US) 2016-05-17 US disclosed
US-9284434-B2 Epoxy resin compositions BLUE CUBE IP LLC (US) 2016-03-15 US disclosed
EP-2621990-B1 THERMOSETTABLE COMPOSITIONS AND THERMOSETS THEREFROM BLUE CUBE IP LLC (US) 2016-02-24 EP disclosed
US-9068039-B2 Thermosettable compositions and thermosets therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2015-06-30 US disclosed
EP-0478918-A2 Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-04-08 EP disclosed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP disclosed
EP-0473935-A2 Curable mixture of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP disclosed
EP-0469492-A2 Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-02-05 EP disclosed
EP-0379055-A2 Mesogenic advanced epoxy compounds THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP disclosed