SCHEMBL9756514

SCHEMBL9756514

O=C(O)c1ccc(P)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.47
ALDH1A1 P00352 5/20 0.46
ALOX15 P16050 1/20 0.46
HNF4A P41235 3/20 0.46
ACMSD Q8TDX5 2/20 0.46
KDM4E B2RXH2 3/20 0.45
MAPT P10636 2/20 0.45
PIM1 P11309 1/20 0.45
GFER P55789 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
DHFR P00374 1/20 0.41
MCL1 Q07820 1/20 0.41
CDC25B P30305 1/20 0.41
ATM Q13315 1/20 0.41
CYP1A2 P05177 2/20 0.41
DCLRE1A Q6PJP8 1/20 0.41
DCLRE1B Q9H816 1/20 0.41
FABP4 P15090 3/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL332581 0.89 ALDH1A1 (0.57) WDR5ALDH1A1ALOX15HNF4AACMSD
SCHEMBL901069 0.85 ACMSD (0.61) WDR5ALDH1A1ALOX15HNF4AACMSD
SCHEMBL9152464 0.79 ACMSD (0.55) WDR5ALDH1A1ALOX15HNF4AACMSD
SCHEMBL12006684 0.79 HNF4A (0.55) WDR5ALDH1A1ALOX15HNF4AACMSD
Biphenyl SCHEMBL9318563 0.78 ALDH1A1 (0.56) ALDH1A1ALOX15HNF4AACMSDKDM4E
SCHEMBL70098 0.78 HNF4A (0.63) WDR5ALDH1A1ALOX15HNF4AACMSD
Salicylic Acid SCHEMBL5703937 0.78 ALDH1A1 (0.72) WDR5ALDH1A1ALOX15HNF4AACMSD
SCHEMBL5820920 0.78 FABP3 (0.54) WDR5ALDH1A1ALOX15HNF4AACMSD
SCHEMBL8422568 0.78 CYP3A4 (0.54) WDR5ALDH1A1ALOX15HNF4AACMSD
SCHEMBL30395913 0.77 WDR5 (0.48) WDR5ALDH1A1ALOX15HNF4AACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104525268-A Organic/inorganic composite two-dimensional catalyst with triphenylphosphine-ruthenium structure and preparation method of catalyst UNIV SHANGHAI 2015-04-22 CN disclosed
EP-0274795-B1 PROCESS FOR THE CARBONYLATION OF OLEFINICALLY UNSATURATED COMPOUNDS WITH A PALLADIUM CATALYST SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-08-21 EP disclosed
US-4960926-A Process for the carbonylation of olefinically unsaturated compounds with a palladium catalyst SHELL OIL COMPANY (US) 1990-10-02 US disclosed
EP-0274795-A2 Process for the carbonylation of olefinically unsaturated compounds with a palladium catalyst SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-07-20 EP disclosed