Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648069 | 1.00 | — | — | |
| Lithium Ion SCHEMBL27351343 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL27595398 | 0.86 | — | — | |
| Water SCHEMBL27700526 | 0.86 | — | — | |
| SCHEMBL27513398 | 0.84 | CA1 (0.57) | — | |
| Water SCHEMBL9336807 | 0.84 | — | — | |
| SCHEMBL27512693 | 0.84 | CA1 (0.57) | — | |
| SCHEMBL11560033 | 0.84 | — | — | |
| SCHEMBL9547 | 0.84 | — | — | |
| SCHEMBL29827705 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111521803-A | Protein probe and application thereof in evaluating specific binding of antigen and antibody | 华南理工大学 | 2020-08-11 | — | — | CN | claimed |
| CN-112469720-B | Dual ATM and DNA-PK inhibitors for use in anti-tumor therapy | 艾科思莱德制药公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-112236423-B | Piperidinyl-3- (aryloxy) propanamides and propionic acid esters | 武田药品工业株式会社 | 2024-02-06 | — | — | CN | disclosed |
| CN-117098767-A | METTL3 modulators | 埃克森特治疗公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-116332873-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116171272-A | Novel VDAC1 inhibitors | 阿巴尔塞奥制药公司 | 2023-05-26 | — | — | CN | disclosed |
| US-10576137-B2 | Oligosialic acid derivatives, methods of manufacture, and immunological uses | CHILDREN'S HOSPITAL RESEARCH CENTER AT OAKLAND (US) | 2020-03-03 | — | — | US | disclosed |
| US-20170056489-A1 | Oligosialic Acid Derivatives, Methods of Manufacture, and Immunological Uses | CHILDREN'S HOSPITAL AND RESEARCH CENTER AT OAKLAND | 2017-03-02 | — | — | US | disclosed |
| US-9333247-B2 | Oligosialic acid derivatives, methods of manufacture, and immunological uses | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) | 2016-05-10 | — | — | US | disclosed |
| US-8642562-B2 | Polysialic acid derivatives, methods of production, and uses in enhancing cancer antigen production and targeting | CHILDREN'S HOSPITAL & RESEARCH CENTER OAKLAND (US) | 2014-02-04 | — | — | US | disclosed |
| EP-0401248-A4 | AFFINITY MATRICES OF MODIFIED POLYSACCHARIDE SUPPORTS | — | 1992-04-15 | — | — | EP | disclosed |
| US-5059654-A | Synthetic polymer; affinity ligand or biologically active molecule; hydrophobic compound, chromatographic separation | CUNO INC. (US) | 1991-10-22 | — | — | US | disclosed |
| EP-0425268-A2 | Phosphazene polymer carrier for biologically active substance | TEIJIN LIMITED (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0401248-A1 | AFFINITY MATRICES OF MODIFIED POLYSACCHARIDE SUPPORTS | Cuno Incorporated (US) | 1990-12-12 | — | — | EP | disclosed |
| CN-1047078-A | Polyamines and polypeptides useful as excitatory amino acid neurotransmitter antagonists and/or calcium channel blockers | PFIZER (US) | 1990-11-21 | — | — | CN | disclosed |
| CN-1038837-A | RECOMBINANT COCCIDIOSIS VACCINES | HOFFMANN LA ROCHE (CH) | 1990-01-17 | — | — | CN | disclosed |
| WO-1989007618-A1 | AFFINITY MATRICES OF MODIFIED POLYSACCHARIDE SUPPORTS | CUNO, INCORPORATED (US) | 1989-08-24 | — | — | WO | disclosed |
| CN-88100378-A | New peptidase inhibitors | — | 1988-10-05 | — | — | CN | disclosed |
| CN-85105798-A | Octahydro- azoles is the preparation method of [4,5-g] quinoline also | — | 1987-01-28 | — | — | CN | disclosed |
| CN-85101547-A | The preparation method and its usage of novel octahydro thiazole [4,5-g] and quinoline compound | — | 1987-01-24 | — | — | CN | disclosed |