Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3332924 | 1.00 | MAPT (0.43) | MAPTTDP1KDM4EHPGDLMNA | |
| SCHEMBL6314505 | 0.84 | KDM4E (0.41) | MAPTKDM4EHPGDLMNAMAPK1 | |
| SCHEMBL6314507 | 0.84 | KDM4E (0.41) | MAPTKDM4EHPGDLMNAMAPK1 | |
| SCHEMBL3301483 | 0.78 | NPC1 (0.40) | MAPTKDM4EHPGDLMNAPOLB | |
| SCHEMBL3301476 | 0.78 | NPC1 (0.40) | MAPTKDM4EHPGDLMNAPOLB | |
| SCHEMBL6321996 | 0.76 | HTR2B (0.35) | MAPTTDP1KDM4EHPGDLMNA | |
| SCHEMBL3300121 | 0.76 | HTR2B (0.35) | MAPTTDP1KDM4EHPGDLMNA | |
| SCHEMBL11963386 | 0.74 | ALDH1A1 (0.37) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL3303995 | 0.74 | NPC1 (0.40) | MAPTKDM4EHPGDLMNAMAPK1 | |
| SCHEMBL3303985 | 0.74 | NPC1 (0.40) | MAPTKDM4EHPGDLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137346-A1 | DESFERRITHIOCIN ANALOGUE ACTINIDE DECORPORATION AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| EP-2101764-A2 | DESFERRITHIOCIN ANALOGUE ACTINIDE DECORPORATION AGENTS | UNIVERSITY OF FLORIDA (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008130395-A2 | DESFERRITHIOCIN ANALOGUE ACTINIDE DECORPORATION AGENTS | UNIVERSITY OF FLORIDA (US) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137346-A1 | DESFERRITHIOCIN ANALOGUE ACTINIDE DECORPORATION AGENTS | TFRC, SLC40A1, FIBP | MAPT 1354/4885TDP1 3081/4885KDM4E 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.